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至今，GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次，处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果，再次证明GenScript 有能力帮助业内科学家Make research easy.

页码: 60/122 每页显示数量

Structural basis for an exceptionally strong preference for asparagine residue at the S2 subsite of Stenotrophomonas maltophilia dipeptidyl peptidase 7

Authors: Akihiro Nakamura, Yoshiyuki Suzuki, Yasumitsu Sakamoto, Saori Roppongi, Chisato Kushibiki, Natsuri Yonezawa, Masato Takahashi, Yosuke Shida, Hiroaki Gouda, Takamasa Nonaka, Nobutada Tanaka, Wataru Ogasawara

Journal: Sci Rep

PubMed ID: 33846449

Doi: 10.1038/s41598-021-86965-x

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Reduced Nucleoprotein Availability Impairs Negative-Sense RNA Virus Replication and Promotes Host Recognition

Authors: Benjamin E Nilsson-Payant, Daniel Blanco-Melo, Skyler Uhl, Beatriz Escudero-Pérez, Silke Olschewski, Patricia Thibault, Maryline Panis, Maria Rosenthal, César Muñoz-Fontela, Benhur Lee, Benjamin R tenOever

Journal: J Virol

PubMed ID: 33568513

Doi: 10.1128/JVI.02274-20

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Synergistic Activation of Antitumor Immunity by a Particulate Therapeutic Vaccine

Authors: Junhua Mai, Zhaoqi Li, Xiaojun Xia, Jingxin Zhang, Jun Li, Haoran Liu, Jianliang Shen, Maricela Ramirez, Feng Li, Zheng Li, Kenji Yokoi, Xuewu Liu, Elizabeth A Mittendorf, Mauro Ferrari, Haifa Shen

Journal: Adv Sci (Weinh)

PubMed ID: 34194942

Doi: 10.1002/advs.202100166

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Myeloid-derived suppressor cells support remyelination in a murine model of multiple sclerosis by promoting oligodendrocyte precursor cell survival, proliferation, and differentiation

Authors: Melero-Jerez C,Fernández-Gómez B,Lebrón-Galán R,Ortega MC,Sánchez-de Lara I,Ojalvo AC,Clemente D,de Castro F

Journal: Glia

PubMed ID: 33217041

Doi: 10.1002/glia.23936

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Intradermal delivery of a synthetic DNA vaccine protects macaques from Middle East respiratory syndrome coronavirus

Authors: Ami Patel, Emma L Reuschel, Ziyang Xu, Faraz I Zaidi, Kevin Y Kim, Dana P Scott, Janess Mendoza, Stephanie Ramos, Regina Stoltz, Friederike Feldmann, Atsushi Okumura, Kimberly Meade-White, Elaine Haddock, Tina Thomas, Rebecca Rosenke, Jamie Lovaglio, Patrick W Hanley, Greg Saturday, Kar Muthumani, Heinz Feldmann, Laurent M Humeau, Kate E Broderick, David B Weiner

Journal: JCI Insight

PubMed ID: 33886507

Doi: 10.1172/jci.insight.146082

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H3K36 methylation reprograms gene expression to drive early gametocyte development in Plasmodium falciparum

Authors: Jessica Connacher, Gabrielle A Josling, Lindsey M Orchard, Janette Reader, Manuel Llinás, Lyn-Marié Birkholtz

Journal: Epigenetics Chromatin

PubMed ID: 33794978

Doi: 10.1186/s13072-021-00393-9

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Dynamic allostery controls the peptide sensitivity of the Ly49C natural killer receptor

Authors: Jiaqi Ma, Cory M Ayres, Lance M Hellman, Jason R Devlin, Brian M Baker

Journal: J Biol Chem

PubMed ID: 33891944

Doi: 10.1016/j.jbc.2021.100686

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Machine learning guided aptamer refinement and discovery

Authors: Ali Bashir, Qin Yang, Jinpeng Wang, Stephan Hoyer, Wenchuan Chou, Cory McLean, Geoff Davis, Qiang Gong, Zan Armstrong, Junghoon Jang, Hui Kang, Annalisa Pawlosky, Alexander Scott, George E Dahl, Marc Berndl, Michelle Dimon, B Scott Ferguson

Journal: Nat Commun

PubMed ID: 33888692

Doi: 10.1038/s41467-021-22555-9

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Nucleoside selectivity of Aspergillus fumigatus nucleoside-diphosphate kinase

Authors: Nguyen S,Jovcevski B,Pukala TL,Bruning JB

Journal: The FEBS journal

PubMed ID: 33089641

Doi: 10.1111/febs.15607

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CD8 T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope display high naive precursor frequency and TCR promiscuity

Authors: Thi H O Nguyen, Louise C Rowntree, Jan Petersen, Brendon Y Chua, Luca Hensen, Lukasz Kedzierski, Carolien E van de Sandt, Priyanka Chaurasia, Hyon-Xhi Tan, Jennifer R Habel, Wuji Zhang, Lilith F Allen, Linda Earnest, Kai Yan Mak, Jennifer A Juno, Kathleen Wragg, Francesca L Mordant, Fatima Amanat, Florian Krammer, Nicole A Mifsud, Denise L Doolan, Katie L Flanagan, Sabrina Sonda, Jasveen Kaur, Linda M Wakim, Glen P Westall, Fiona James, Effie Mouhtouris, Claire L Gordon, Natasha E Holmes, Olivia C Smibert, Jason A Trubiano, Allen C Cheng, Peter Harcourt, Patrick Clifton, Jeremy Chase Crawford, Paul G Thomas, Adam K Wheatley, Stephen J Kent, Jamie Rossjohn, Joseph Torresi, Katherine Kedzierska

Journal: Immunity

PubMed ID: 33951417

Doi: 10.1016/j.immuni.2021.04.009

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