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Heparin promotes fibrillation of most phenol-soluble modulin virulence peptides from Staphylococcus aureus
Authors: Zahra Najarzadeh, Masihuz Zaman, Vita Sereikaite, Kristian Strømgaard, Maria Andreasen, Daniel E Otzen
Journal: J Biol Chem
PubMed ID: 34270957
Doi: 10.1016/j.jbc.2021.100953
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A Covalent Calmodulin Inhibitor as a Tool to Study Cellular Mechanisms of K-Ras-Driven Stemness
Authors: Sunday Okutachi, Ganesh Babu Manoharan, Alexandros Kiriazis, Christina Laurini, Marie Catillon, Frank McCormick, Jari Yli-Kauhaluoma, Daniel Abankwa
Journal: Front Cell Dev Biol
PubMed ID: 34307350
Doi: 10.3389/fcell.2021.665673
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The identification and structural analysis of potential 14-3-3 interaction sites on the bone regulator protein Schnurri-3
Authors: Lorenzo Soini, Seppe Leysen, Tom Crabbe, Jeremy Davis, Christian Ottmann
Journal: Acta Crystallogr F Struct Biol Commun
PubMed ID: 34341191
Doi: 10.1107/S2053230X21006658
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Structural insights into hormone recognition by the human glucose-dependent insulinotropic polypeptide receptor
Authors: Fenghui Zhao, Chao Zhang, Qingtong Zhou, Kaini Hang, Xinyu Zou, Yan Chen, Fan Wu, Qidi Rao, Antao Dai, Wanchao Yin, Dan-Dan Shen, Yan Zhang, Tian Xia, Raymond C Stevens, H Eric Xu, Dehua Yang, Lihua Zhao, Ming-Wei Wang
Journal: Elife
PubMed ID: 34254582
Doi: 10.7554/eLife.68719
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CDK1 controls CHMP7-dependent nuclear envelope reformation
Authors: Alberto T Gatta, Yolanda Olmos, Caroline L Stoten, Qu Chen, Peter B Rosenthal, Jeremy G Carlton
Journal: Elife
PubMed ID: 34286694
Doi: 10.7554/eLife.59999
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A stealth antigen SPESP1, which is epigenetically silenced in tumors, is a suitable target for cancer immunotherapy
Authors: Akemi Kosaka, Yuki Yajima, Mayumi Hatayama, Katsuya Ikuta, Takaaki Sasaki, Noriko Hirai, Syunsuke Yasuda, Marino Nagata, Ryusuke Hayashi, Shohei Harabuchi, Kenzo Ohara, Mizuho Ohara, Takumi Kumai, Kei Ishibashi, Yui Hirata-Nozaki, Toshihiro Nagato, Kensuke Oikawa, Yasuaki Harabuchi, Esteban Celis, Toshikatsu Okumura, Yoshinobu Ohsaki, Hiroya Kobayashi, Takayuki Ohkuri
Journal: Cancer Sci
PubMed ID: 34009705
Doi: 10.1111/cas.14973
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Novel Bisubstrate Inhibitors for Protein N-Terminal Acetyltransferase D
Authors: Youchao Deng, Sunbin Deng, Yi-Hsun Ho, Sarah M Gardner, Zhi Huang, Ronen Marmorstein, Rong Huang
Journal: J Med Chem
PubMed ID: 34110812
Doi: 10.1021/acs.jmedchem.1c00141
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A novel mouse AAV6 hACE2 transduction model of wild-type SARS-CoV-2 infection studied using synDNA immunogens
Authors: Ebony N Gary, Bryce M Warner, Elizabeth M Parzych, Bryan D Griffin, Xizhou Zhu, Nikesh Tailor, Nicholas J Tursi, Mable Chan, Mansi Purwar, Robert Vendramelli, Jihae Choi, Kathy L Frost, Sophia Reeder, Kevin Liaw, Edgar Tello, Ali R Ali, Kun Yun, Yanlong Pei, Sylvia P Thomas, Amira D Rghei, Matthew M Guilleman, Kar Muthumani, Trevor Smith, Sarah K Wootton, Ami Patel, David B Weiner, Darwyn Kobasa
Journal: iScience
PubMed ID: 34124612
Doi: 10.1016/j.isci.2021.102699
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The ORF8 protein of SARS-CoV-2 mediates immune evasion through down-regulating MHC-Ι
Authors: Yiwen Zhang, Yingshi Chen, Yuzhuang Li, Feng Huang, Baohong Luo, Yaochang Yuan, Baijin Xia, Xiancai Ma, Tao Yang, Fei Yu, Jun Liu, Bingfeng Liu, Zheng Song, Jingliang Chen, Shumei Yan, Liyang Wu, Ting Pan, Xu Zhang, Rong Li, Wenjing Huang, Xin He, Fei Xiao, Junsong Zhang, Hui Zhang
Journal: Proc Natl Acad Sci U S A
PubMed ID: 34021074
Doi: 10.1073/pnas.2024202118
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In vitro reconstitution of Sgk3 activation by phosphatidylinositol 3-phosphate
Authors: Daniel Pokorny, Linda Truebestein, Kaelin D Fleming, John E Burke, Thomas A Leonard
Journal: J Biol Chem
PubMed ID: 34181950
Doi: 10.1016/j.jbc.2021.100919
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