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至今，GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次，处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果，再次证明GenScript 有能力帮助业内科学家Make research easy.

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Crizotinib acts as ABL1 inhibitor combining ATP-binding with allosteric inhibition and is active against native BCR-ABL1 and its resistance and compound mutants BCR-ABL1 and BCR-ABL1

Authors: Afsar Ali Mian, Isabella Haberbosch, Hazem Khamaisie, Abed Agbarya, Larissa Pietsch, Elizabeh Eshel, Dally Najib, Claudia Chiriches, Oliver Gerhard Ottmann, Oliver Hantschel, Ricardo M Biondi, Martin Ruthardt, Jamal Mahajna

Journal: Ann Hematol

PubMed ID: 34110462

Doi: 10.1007/s00277-020-04357-z

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Therapeutic Potential of HLA-I Polyreactive mAbs Mimicking the HLA-I Polyreactivity and Immunoregulatory Functions of IVIg

Authors: Mepur H Ravindranath, Fatiha El Hilali, Edward J Filippone

Journal: Vaccines (Basel)

PubMed ID: 34205517

Doi: 10.3390/vaccines9060680

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A vaccine inducing solely cytotoxic T lymphocytes fully prevents Zika virus infection and fetal damage

Authors: Frank Gambino, Wanbo Tai, Denis Voronin, Yi Zhang, Xiujuan Zhang, Juan Shi, Xinyi Wang, Ning Wang, Lanying Du, Liang Qiao

Journal: Cell Rep

PubMed ID: 33979612

Doi: 10.1016/j.celrep.2021.109107

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IgE-activated mast cells enhance TLR4-mediated antigen-specific CD4 T cell responses

Authors: Binh L Phong, Shaina J D'Souza, Robin L Baudier, Eric Wu, Victoria E Immethun, David L Bauer, James B McLachlan

Journal: Sci Rep

PubMed ID: 33958642

Doi: 10.1038/s41598-021-88956-4

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Minimally invasive brain injections for viral-mediated transgenesis: New tools for behavioral genetics in sticklebacks

Authors: Noelle James, Alison Bell

Journal: PLoS ONE

PubMed ID: 33999965

Doi: 10.1371/journal.pone.0251653

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S-acylation of P2K1 mediates extracellular ATP-induced immune signaling in Arabidopsis

Authors: Dongqin Chen, Fengsheng Hao, Huiqi Mu, Nagib Ahsan, Jay J Thelen, Gary Stacey

Journal: Nat Commun

PubMed ID: 33980819

Doi: 10.1038/s41467-021-22854-1

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Qki activates Srebp2-mediated cholesterol biosynthesis for maintenance of eye lens transparency

Authors: Seula Shin, Hao Zhou, Chenxi He, Yanjun Wei, Yunfei Wang, Takashi Shingu, Ailiang Zeng, Shaobo Wang, Xin Zhou, Hongtao Li, Qiang Zhang, Qinling Mo, Jiafu Long, Fei Lan, Yiwen Chen, Jian Hu

Journal: Nat Commun

PubMed ID: 34021134

Doi: 10.1038/s41467-021-22782-0

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Lipid-nanoparticle-encapsulated mRNA vaccines induce protective memory CD8 T cells against a lethal viral infection

Authors: Cory J Knudson, Pedro Alves-Peixoto, Hiromi Muramatsu, Colby Stotesbury, Lingjuan Tang, Paulo J C Lin, Ying K Tam, Drew Weissman, Norbert Pardi, Luis J Sigal

Journal: Mol Ther

PubMed ID: 33992803

Doi: 10.1016/j.ymthe.2021.05.011

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Qki regulates myelinogenesis through Srebp2-dependent cholesterol biosynthesis

Authors: Xin Zhou, Seula Shin, Chenxi He, Qiang Zhang, Matthew N Rasband, Jiangong Ren, Congxin Dai, Rocío I Zorrilla-Veloz, Takashi Shingu, Liang Yuan, Yunfei Wang, Yiwen Chen, Fei Lan, Jian Hu

Journal: Elife

PubMed ID: 33942715

Doi: 10.7554/eLife.60467

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The human tRNA-guanine transglycosylase displays promiscuous nucleobase preference but strict tRNA specificity

Authors: Claire Fergus, Mashael Al-Qasem, Michelle Cotter, Ciara M McDonnell, Emiliano Sorrentino, Franciane Chevot, Karsten Hokamp, Mathias O Senge, John M Southern, Stephen J Connon, Vincent P Kelly

Journal: Nucleic Acids Res

PubMed ID: 34009357

Doi: 10.1093/nar/gkab289

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