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Engineered ipilimumab variants that bind human and mouse CTLA-4

Authors: Brett Robison 1, S J Diong 1, Anusha Kumar 1, Thomas M Moon , Olin Chang , Bryant Chau , Christine Bee , Ishita Barman , Arvind Rajpal , Alan J Korman , Sean West , Pavel Strop , Peter S Lee

Journal: MAbs

PubMed ID: 39849917

Doi: 10.1080/19420862.2025.2451296

Products & Services: Combinatorial DNA Libraries

Proteolysis-triggered RNA Interference for Mitochondrial Iron Dyshomeostasis to Activate Antitumor Immunity in Hepatic Carcinoma

Authors: Shi-Man Zhang, Xiao-Kang Jin, Hong Chen, Yu-Zhang Wang, Jun-Long Liang, Jun Feng, Wei-Hai Chen, Xian-Zheng Zhang

Journal: ADVANCED MATERIALS

PubMed ID: 40757917

Doi: 10.1002/adma.202508457

Products & Services: Catalog Peptides

Aligned Electrospun Fibers Inducing Cell and Nuclear Morphology Remodeling via Ras-Associated Protein 1/Yes-Associated Protein Signaling Enhances Bone Regeneration

Authors: Shengjie Jiang, Jialiang Zhou, Cancan Zhao, Liyun Wang, Zeyu Fu, Mazaher Gholipourmalekabadi, Xudong Wang, Changyong Yuan, Kaili Lin

Journal: Advanced Fiber Materials

Doi: 10.1007/s42765-025-00596-9

Products & Services: Catalog Antibody

In situ proximity labeling of proteins associated with circRNA and RNA G-quadruplexes

Authors: Jing Mo, Zonggui Chen, Manman Cui, Xin Fang, Ruihan Li, Shanshan Qin, Zhenlin Zhou, Mei Sun, Jinjun Wu, Chuan He, Fang Wang, Haojian Zhang, Xiang Zhou, Xiaocheng Weng

Journal: Nature Chemical Biology

PubMed ID: 40775047

Doi: 10.1038/s41589-025-01993-2

Products & Services: Proteins, Expression, Isolation and Analysis

Bioorthogonal Non-Canonical Amino Acid Tagging (BONCAT) to detect newly synthesized proteins in cells and their secretome

Authors: Elizabeth P. Anim, Justin Mezzanotte, Siwei Chu, Ursula Stochaj

Journal: PLoS One

PubMed ID: 40811457

Products & Services: Proteins, Expression, Isolation and Analysis

Structural basis for E4 enzyme Ufd2-catalyzed K48/K29 branched ubiquitin chains

Authors: Zebin Tong, Xiangwei Wu, Hongyi Cai, Shidian Wu, Tianyi Zhang, Zhiheng Deng, Ziyu Xu, Rujing Yuan, Huasong Ai, Lei Liu, Man Pan

Journal: Nature Chemical Biology

PubMed ID: 40817136

Doi: 10.1038/s41589-025-01985-2

Products & Services: Gene Synthesis

FlaB-expressing bacterial uter membrane vesicles vaccine mediating anti-tumor immune response via promoting DCs activation and lymph nodes-homing

Authors: Kaiwei Wang, Chang Xu, Minming Chen, Yifan Yan, Nanhui Liu, Changhao Zhao, Bo Liu, Yanbin Liu, Jianjiang Chen, Xiaoliang Ding, Yicong Bian, Lin Song, Xuyu Bian, Yumin Wu, Liyan Miao, Zhuang Liu

Journal: Nano Research

PubMed ID: 40817136

Doi: 10.26599/NR.2025.94907612

Products & Services: Proteins, Expression, Isolation and Analysis

Lung metastasis and recurrence is mitigated by CARmacrophages, in-situ-generated from mRNA delivered by small extracellular vesicles

Authors: Yuchen Xiao, Tianchuan Zhu, Zhenxing Chen, Xi Huang

Journal: Nature Communications

PubMed ID: 40759657

Doi: 10.1038/s41467-025-62506-2

Products & Services: Custom DNA/RNA Oligos

Exomeres From Adventitial Fibroblasts of Spontaneously Hypertensive Rats Promote Vascular Remodelling via Transferring Osteopontin.

Authors: Jing-Xiao Wang, Xiao-Yu Xu, Hong-Ke Dong, Yi-Ming Wang, Min Dai, Bing Zhou, Yue-Hua Li, Guo-Qing Zhu, Xiao-Qing Xiong