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Exploration of benzofuran-based compounds as potent and selective Plasmodium falciparum glycogen synthase kinase-3 (PfGSK-3) inhibitors
Authors: Chantalle Moolman, Rencia van der Sluis, Richard M Beteck, Lesetja J Legoabe
Journal: Bioorg Chem
PubMed ID: 33813310
Doi: 10.1016/j.bioorg.2021.104839
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Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines
Authors: Alexandra C Walls, Marcos C Miranda, Minh N Pham, Alexandra Schäfer, Allison Greaney, Prabhu S Arunachalam, Mary-Jane Navarro, M Alejandra Tortorici, Kenneth Rogers, Megan A O'Connor, Lisa Shireff, Douglas E Ferrell, Natalie Brunette, Elizabeth Kepl, John Bowen, Samantha K Zepeda, Tyler Starr, Ching-Lin Hsieh, Brooke Fiala, Samuel Wrenn, Deleah Pettie, Claire Sydeman, Max Johnson, Alyssa Blackstone, Rashmi Ravichandran, Cassandra Ogohara, Lauren Carter, Sasha W Tilles, Rino Rappuoli, Derek T O'Hagan, Robbert Van Der Most, Wesley C Van Voorhis, Jason S McLellan, Harry Kleanthous, Timothy P Sheahan, Deborah H Fuller, Francois Villinger, Jesse Bloom, Bali Pulendran, Ralph Baric, Neil King, David Veesler
Journal: biorxiv
PubMed ID: 33758839
Doi: 10.1101/2021.03.15.435528
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Stabilization of Damaged Articular Cartilage with Hydrogel-Mediated Reinforcement and Sealing
Authors: Jay M Patel, Claudia Loebel, Kamiel S Saleh, Brian C Wise, Edward D Bonnevie, Liane M Miller, James L Carey, Jason A Burdick, Robert L Mauck
Journal: Adv Healthc Mater
PubMed ID: 33738988
Doi: 10.1002/adhm.202100315
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SOCS-1 inhibition of type I interferon restrains Staphylococcus aureus skin host defense
Authors: Nathan Klopfenstein, Stephanie L Brandt, Sydney Castellanos, Matthias Gunzer, Amondrea Blackman, C Henrique Serezani
Journal: PLoS Pathog
PubMed ID: 33690673
Doi: 10.1371/journal.ppat.1009387
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Exploiting albumin as a mucosal vaccine chaperone for robust generation of lung-resident memory T cells
Authors: Kavya Rakhra, Wuhbet Abraham, Chensu Wang, Kelly D Moynihan, Na Li, Nathan Donahue, Alexis D Baldeon, Darrell J Irvine
Journal: Sci Immunol
PubMed ID: 33741657
Doi: 10.1126/sciimmunol.abd8003
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The survival and function of IL-10-producing regulatory B cells are negatively controlled by SLAMF5
Authors: Lihi Radomir, Matthias P Kramer, Michal Perpinial, Nofar Schottlender, Stav Rabani, Keren David, Anna Wiener, Hadas Lewinsky, Shirly Becker-Herman, Rina Aharoni, Ron Milo, Claudia Mauri, Idit Shachar
Journal: Nat Commun
PubMed ID: 33767202
Doi: 10.1038/s41467-021-22230-z
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Daily rewiring of a neural circuit generates a predictive model of environmental light
Authors: Bryan J Song, Slater J Sharp, Dragana Rogulja
Journal: Sci Adv
PubMed ID: 33762336
Doi: 10.1126/sciadv.abe4284
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Production and purification of TRPV2 and TRPV5 for structural and functional studies
Authors: Edwin C Fluck, Ruth A Pumroy, Vera Y Moiseenkova-Bell
Journal: Methods Enzymol
PubMed ID: 34099181
Doi: 10.1016/bs.mie.2021.02.007
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Assembly of a dsRNA synthesizing complex: RNA-DEPENDENT RNA POLYMERASE 2 contacts the largest subunit of NUCLEAR RNA POLYMERASE IV
Authors: Vibhor Mishra, Jasleen Singh, Feng Wang, Yixiang Zhang, Akihito Fukudome, Jonathan C Trinidad, Yuichiro Takagi, Craig S Pikaard
Journal: Proc Natl Acad Sci U S A
PubMed ID: 33753485
Doi: 10.1073/pnas.2019276118
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Selective manipulation of peptide orientation on hexagonal boron nitride nanosheets
Authors: Nermina Brljak, Ruitao Jin, Tiffany R Walsh, Marc R Knecht
Journal: Nanoscale
PubMed ID: 33725079
Doi: 10.1039/d1nr00609f
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