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Mapping enzyme catalysis with metabolic biosensing

Authors: Linfeng Xu, Kai-Chun Chang, Emory M Payne, Cyrus Modavi, Leqian Liu, Claire M Palmer, Nannan Tao, Hal S Alper, Robert T Kennedy, Dale S Cornett, Adam R Abate

Journal: Nat Commun

PubMed ID: 34815408

Doi: 10.1038/s41467-021-27185-9

Products & Services: Mutagenesis Services

Vectored antibody gene delivery restores host B and T cell control of persistent viral infection

Authors: Yusuf I Ertuna, Benedict Fallet, Anna-Friederike Marx, Mirela Dimitrova, Anna Lena Kastner, Ingrid Wagner, Doron Merkler, Daniel D Pinschewer

Journal: Cell Rep

PubMed ID: 34852228

Doi: 10.1016/j.celrep.2021.110061

Products & Services: Mutagenesis Services

FCRL1 Regulates B Cell Receptor-Induced ERK Activation through GRB2

Authors: Jenna M DeLuca, Maegan K Murphy, Xin Wang, Timothy J Wilson

Journal: J Immunol

PubMed ID: 34697226

Doi: 10.4049/jimmunol.2100218

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Systemic and mucosal immune profiling in asymptomatic and symptomatic SARS-CoV-2-infected individuals reveal unlinked immune signatures

Authors: Supriya Ravichandran, Gabrielle Grubbs, Juanjie Tang, Youri Lee, Chang Huang, Hana Golding, Surender Khurana

Journal: Sci Adv

PubMed ID: 34644111

Doi: 10.1126/sciadv.abi6533

Products & Services: Mutagenesis Services

F-NMR reveals substrate specificity of CYP121A1 in Mycobacterium tuberculosis

Authors: Christopher S Campomizzi, George E Ghanatios, D Fernando Estrada

Journal: J Biol Chem

PubMed ID: 34634307

Doi: 10.1016/j.jbc.2021.101287

Products & Services: Mutagenesis Services

Human Monoclonal Antibodies against NS1 Protein Protect against Lethal West Nile Virus Infection

Authors: Alex W Wessel, Michael P Doyle, Taylor B Engdahl, Jessica Rodriguez, James E Crowe, Michael S Diamond

Journal: MBio

PubMed ID: 34634945

Doi: 10.1128/mBio.02440-21

Products & Services: Mutagenesis Services

Determining folding and binding properties of the C-terminal SH2 domain of SHP2

Authors: Caterina Nardella, Francesca Malagrinò, Livia Pagano, Serena Rinaldo, Stefano Gianni, Angelo Toto

Journal: Protein Sci

PubMed ID: 34605082

Doi: 10.1002/pro.4201

Products & Services: Mutagenesis Services

Functional Assessment of Missense Variants in the ABCC6 Gene Implicated in Pseudoxanthoma Elasticum, a Heritable Ectopic Mineralization Disorder

Authors: Luke Kowal, Jianhe Huang, Hongbin Luo, Jagmohan Singh, Adam E Snook, Jouni Uitto, Qiaoli Li

Journal: J Invest Dermatol

PubMed ID: 34597610

Doi: 10.1016/j.jid.2021.08.435

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complementary DNA is enriched in atrophic macular degeneration and triggers retinal pigmented epithelium toxicity via cytosolic innate immunity

Authors: Shinichi Fukuda, Siddharth Narendran, Akhil Varshney, Yosuke Nagasaka, Shao-Bin Wang, Kameshwari Ambati, Ivana Apicella, Felipe Pereira, Benjamin J Fowler, Tetsuhiro Yasuma, Shuichiro Hirahara, Reo Yasuma, Peirong Huang, Praveen Yerramothu, Ryan D Makin, Mo Wang, Kirstie L Baker, Kenneth M Marion, Xiwen Huang, Elmira Baghdasaryan, Meenakshi Ambati, Vidya L Ambati, Daipayan Banerjee, Vera L Bonilha, Genrich V Tolstonog, Ulrike Held, Yuichiro Ogura, Hiroko Terasaki, Tetsuro Oshika, Deepak Bhattarai, Kyung Bo Kim, Sanford H Feldman, J Ignacio Aguirre, David R Hinton, Nagaraj Kerur, Srinivas R Sadda, Gerald G Schumann, Bradley D Gelfand, Jayakrishna Ambati

Journal: Sci Adv

PubMed ID: 34586848

Doi: 10.1126/sciadv.abj3658

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TRIM25 inhibits infectious bursal disease virus replication by targeting VP3 for ubiquitination and degradation

Authors: Suyan Wang, Mengmeng Yu, Aijing Liu, Yuanling Bao, Xiaole Qi, Li Gao, Yuntong Chen, Peng Liu, Yulong Wang, Lixiao Xing, Lingzhai Meng, Yu Zhang, Linjin Fan, Xinyi Li, Qing Pan, Yanping Zhang, Hongyu Cui, Kai Li, Changjun Liu, Xijun He, Yulong Gao, Xiaomei Wang

Journal: PLoS Pathog

PubMed ID: 34516573

Doi: 10.1371/journal.ppat.1009900

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