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Engineering of an Avidity-Optimized CD19-Specific Parallel Chimeric Antigen Receptor That Delivers Dual CD28 and 4-1BB Co-Stimulation
Authors: Leena Halim, Kushal K Das, Daniel Larcombe-Young, Adam Ajina, Andrea Candelli, Reuben Benjamin, Richard Dillon, David M Davies, John Maher
Journal: Front Immunol
PubMed ID: 35222427
Doi: 10.3389/fimmu.2022.836549
Products & Services: Mutagenesis Services   
Engineering of an Avidity-Optimized CD19-Specific Parallel Chimeric Antigen Receptor That Delivers Dual CD28 and 4-1BB Co-Stimulation
Authors: Leena Halim, Kushal K Das, Daniel Larcombe-Young, Adam Ajina, Andrea Candelli, Reuben Benjamin, Richard Dillon, David M Davies, John Maher
Journal: Front Immunol
PubMed ID: 35222427
Doi: 10.3389/fimmu.2022.836549
Products & Services: Mutagenesis Services   
Channelopathy-causing mutations in the SA/SB and HA/HB helices of K23 and K31 channels alter their apparent Ca sensitivity
Authors: Razan Orfali, Young-Woo Nam, Hai Minh Nguyen, Mohammad Asikur Rahman, Grace Yang, Meng Cui, Heike Wulff, Miao Zhang
Journal: Cell Calcium
PubMed ID: 35030515
Doi: 10.1016/j.ceca.2022.102538
Products & Services: Mutagenesis Services   
Mapping Critical Residues in ATG11's Coiled-Coil 2 Domain that Block Multiple Interactions and Disrupt Selective Autophagy
Authors: Mitchell D Meyer, Jasmine Winzeler, Sophia M Taylor, Alex Kilgore, Kimberly Edicha, Chase Chitwood, Zachary Spearin, S K Nadia Rahman Silvia, Ronith Chakraborty, Jesse E Smith, Bridget Kennedy, Carson Zois, Hayley Cawthon, Mukiri Gilruth, Steven K Backues
Journal: Front Cell Dev Biol
PubMed ID: 35118068
Doi: 10.3389/fcell.2021.775364
Products & Services: Mutagenesis Services   
Vps501, a novel vacuolar SNX-BAR protein cooperates with the SEA complex to regulate TORC1 signaling
Authors: Shreya Goyal, Verónica A Segarra, Aaron M Stetcher, Andrew W Truman, Adam M Reitzel, Richard J Chi
Journal: Traffic
PubMed ID: 35098628
Doi: 10.1111/tra.12833
Products & Services: Mutagenesis Services   
Antibody variable sequences have a pronounced effect on cellular transport and plasma half-life
Authors: Algirdas Grevys, Rahel Frick, Simone Mester, Karine Flem-Karlsen, Jeannette Nilsen, Stian Foss, Kine Marita Knudsen Sand, Thomas Emrich, Jens Andre Alexander Fischer, Victor Greiff, Inger Sandlie, Tilman Schlothauer, Jan Terje Andersen
Journal: iScience
PubMed ID: 35118359
Doi: 10.1016/j.isci.2022.103746
Products & Services: Mutagenesis Services   
Channelopathy-causing mutations in the S45A/S45B and HA/HB helices of KCa2.3 and KCa3.1 channels alter their apparent Ca2+ sensitivity
Authors: Razan Orfali, Young-Woo Nam, Hai Minh Nguyen, Mohammad Asikur Rahman, Grace Yang, Meng Cui, Heike Wulff, Miao Zhang
Journal: Cell Calcium
Doi: doi.org/10.1016/j.ceca.2022.102538
Products & Services: Mutagenesis Services   
A small RNA that cooperatively senses two stacked metabolites in one pocket for gene control
Authors: Griffin M Schroeder, Chapin E Cavender , Maya E Blau, Jermaine L Jenkins, David H Mathews, Joseph E Wedekind
Journal: Nat Commun
PubMed ID: 35017488
Doi: 10.1038/s41467-021-27790-8
Products & Services: Mutagenesis Services   PCR Cloning and Subcloning   
Overcoming tumor heterogeneity by ex vivo arming of T cells using multiple bispecific antibodies
Authors: Jeong A Park, Nai-Kong V Cheung
Journal: J Immunother Cancer
PubMed ID: 35086947
Doi: 10.1136/jitc-2021-003771
Products & Services: Mutagenesis Services   
pVHL-mediated SMAD3 degradation suppresses TGF-β signaling
Authors: Jun Zhou , Yasamin Dabiri , Rodrigo A Gama-Brambila, Shahrouz Ghafoory , Mukaddes Altinbay , Arianeb Mehrabi , Mohammad Golriz , Biljana Blagojevic , Stefanie Reuter , Kang Han , Anna Seidel , Ivan Đikić , Stefan Wölfl , Xinlai Cheng
Journal: J Cell Biol
PubMed ID: 34860252
Doi: 10.1083/jcb.202012097

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