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Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody

Authors: Asokan M, Dias J, Liu C, Maximova A, Ernste K, Pegu A, McKee K, Shi W, Chen X, Almasri C, Promsote W, Ambrozak DR, Gama L, Hu J, Douek DC, Todd JP, Lifson JD, Fourati S, Sekaly RP, Crowley AR, Ackerman ME, Ko SH, Kilam D, Boritz EA, Liao LE, Best K, Perelson AS, Mascola JR, Koup RA

Journal: Proceedings of the National Academy of Sciences of the United States of America

PubMed ID: 32690707

Doi: 10.1073/pnas.2008236117

Products & Services: Mutagenesis Services

Pharmacological Characterization of a Betaine/GABA Transporter 1 (BGT1) Inhibitor Displaying an Unusual Biphasic Inhibition Profile and Anti‑seizure Effects

Authors: Maria E K Lie , Stefanie Kickinger , Jonas Skovgaard-Petersen , Gerhard F Ecker , Rasmus P Clausen , Arne Schousboe , H Steve White , Petrine Wellendorph

Journal: Neurochem Res

PubMed ID: 32248400

Doi: 10.1007/s11064-020-03017-y

Products & Services: Mutagenesis Services

Mapping the binding site of C1-inhibitor for polyanion cofactors

Authors: Lilian Hor, Jing Pan, James C Whisstock, Robert N Pike, Lakshmi C Wijeyewickrema

Journal: Mol Immunol

PubMed ID: 32717572

Doi: 10.1016/j.molimm.2020.06.018

Products & Services: Mutagenesis Services

Protein Modifications Critical for Myonectin/Erythroferrone Secretion and Oligomer Assembly

Authors: Stewart AN, Little HC, Clark DJ, Zhang H, Wong GW

Journal: Biochemistry

PubMed ID: 32602701

Doi: 10.1021/acs.biochem.0c00461

Products & Services: Mutagenesis Services

Human Papillomavirus 16 E7 Promotes EGFR/PI3K/AKT1/NRF2 Signaling Pathway Contributing to PIR/NF-κB Activation in Oral Cancer Cells

Authors: Diego Carrillo-Beltrán , Juan P Muñoz , Nahir Guerrero-Vásquez , Rancés Blanco , Oscar León , Vanesca de Souza Lino , Julio C Tapia , Edio Maldonado , Karen Dubois-Camacho , Marcela A Hermoso , Alejandro H Corvalán , Gloria M Calaf , Enrique Boccardo , Francisco Aguayo

Journal: Cancers (Basel)

PubMed ID: PMC7409273

Doi: 10.3390/cancers12071904

Products & Services: ORF cDNA Clones/MolecularCloud Mutagenesis Services

Mechanism of Inward Proton Transport in an Antarctic Microbial Rhodopsin

Authors: Andrew Harris, Michalis Lazaratos, Malte Siemers, Ethan Watt, Anh Hoang, Sahoko Tomida , Luiz Schubert, Mattia Saita , Joachim Heberle, Yuji Furutani , Hideki Kandori, Ana-Nicoleta Bondar, Leonid S Brown

Journal: J Phys Chem B

PubMed ID: 32436389

Doi: 10.1021/acs.jpcb.0c02767

Products & Services: Mutagenesis Services Gene Synthesis

Peptides containing the PCNA interacting motif APIM bind to the β-clamp and inhibit bacterial growth and mutagenesis

Authors: Nedal A, Ræder SB, Dalhus B, Helgesen E, Forstrøm RJ, Lindland K, Sumabe BK, Martinsen JH, Kragelund BB, Skarstad K, Bjørås M, Otterlei M

Journal: Nucleic Acids Research

PubMed ID: 32347931

Doi: 10.1093/nar/gkaa278

Products & Services: Mutagenesis Services

Aquaporin-7: A Dynamic Aquaglyceroporin With Greater Water and Glycerol Permeability Than Its Bacterial Homolog GlpF

Authors: Fraser J Moss, Paween Mahinthichaichan, David T Lodowski, Thomas Kowatz, Emad Tajkhorshid, Andreas Engel, Walter F Boron, Ardeschir Vahedi-Faridi

Journal: Front Physiol

PubMed ID: 32695023

Doi: 10.3389/fphys.2020.00728

Products & Services: Gene Synthesis Plasmid DNA Preparation Mutagenesis Services

Mapping glycan-mediated galectin-3 interactions by live cell proximity labeling

Authors: Eugene Joeh, Timothy O’Leary, Weichao Li, Richard Hawkins, Jonathan R. Hung, Christopher G. Parker, Mia L. Huang

Journal: biorxiv

Doi: 10.1101/2020.05.09.058586

Products & Services: Plasmid DNA Preparation Mutagenesis Services

Desaturase specificity is controlled by the physicochemical properties of a single amino acid residue in the substrate binding tunnel

Authors: Aleš Buček, Mario Vazdar, Michal Tupec, Aleš Svatoš, IvaPichová

Journal: Computational and Structural Biotechnology Journal