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Cryo-EM structure of the human Kv3.1 channel reveals gating control by the cytoplasmic T1 domain

Authors: Gamma Chi , Qiansheng Liang , Akshay Sridhar , John B Cowgill , Kasim Sader , Mazdak Radjainia , Pu Qian , Pablo Castro-Hartmann , Shayla Venkaya , Nanki Kaur Singh , Gavin McKinley , Alejandra Fernandez-Cid , Shubhashish M M Mukhopadhyay , Nicola A Burgess-Brown , Lucie Delemotte , Manuel Covarrubias , Katharina L Dürr

Journal: Nat Commun

PubMed ID: 35840580

Doi: 10.1038/s41467-022-29594-w

Products & Services: Plasmid DNA Preparation

Structural, functional, and immunogenicity implications of F9 gene recoding

Authors: Upendra K Katneni, Aikaterini Alexaki, Ryan C Hunt, Nobuko Hamasaki-Katagiri, Gaya K Hettiarachchi, Jacob M Kames, Joseph R McGill, David D Holcomb, John C Athey, Brian Lin, Leonid A Parunov, Tal Kafri, Qi Lu, Robert Peters, Mikhail V Ovanesov, Darón I Freedberg, Haim Bar, Anton A Komar, Zuben E Sauna, Chava Kimchi-Sarfaty

Journal: Blood Adv

PubMed ID: 35413099

Doi: 10.1182/bloodadvances.2022007094

Products & Services: Plasmid DNA Preparation

A biepitope, adjuvant-free, self-assembled influenza nanovaccine provides cross-protection against H3N2 and H1N1 viruses in mice

Authors: Yongbo Qiao, YaXin Zhang, Jie Chen, Shenghui Jin, Yaming Shan

Journal: Nano Res

PubMed ID: 35911479

Doi: 10.1007/s12274-022-4482-4

Products & Services: Plasmid DNA Preparation

Neoantigen Identification and Response to Adoptive Cell Transfer in Anti-PD-1 Naïve and Experienced Patients with Metastatic Melanoma

Authors: Shoshana T Levi, Amy R Copeland, Shirley Nah, Jessica S Crystal, Gabriel D Ivey, Almin Lalani, Mohammad Jafferji, Bradley S White, Neilesh B Parikh, Vid Leko, Sri Krishna, Frank Lowery, Todd D Prickett, Jared J Gartner, Li Jia, Yong F Li, Abraham Sachs, Sivasish Sindiri, Welles Robinson, Billel Gasmi, James C Yang, Stephanie L Goff, Steven A Rosenberg, Paul F Robbins

Journal: Clin Cancer Res

PubMed ID: 35247926

Doi: 10.1158/1078-0432.CCR-21-4499

Products & Services: Plasmid DNA Preparation

N-methyl-pseudouridine is incorporated with higher fidelity than pseudouridine in synthetic RNAs

Authors: Tien-Hao Chen, Vladimir Potapov, Nan Dai, Jennifer L Ong, Bijoyita Roy

Journal: Sci Rep

PubMed ID: 35906281

Doi: 10.1038/s41598-022-17249-1

Products & Services: Plasmid DNA Preparation

SARS-CoV-2 Delta spike protein enhances the viral fusogenicity and inflammatory cytokine production

Authors: Zhujun Ao, Maggie Jing Ouyang, Titus Abiola Olukitibi, Xiaojian Yao

Journal: iScience

PubMed ID: 35854977

Doi: 10.1016/j.isci.2022.104759

Products & Services: Plasmid DNA Preparation

Effective Functional Immunogenicity of a DNA Vaccine Combination Delivered via In Vivo Electroporation Targeting Malaria Infection and Transmission

Authors: Yi Cao , Clifford T H Hayashi , Fidel Zavala , Abhai K Tripathi , Hayk Simonyan , Colin N Young , Leor C Clark , Yukari Usuda , Jacob M Van Parys , Nirbhay Kumar

Journal: Vaccines (Basel)

PubMed ID: 35891298

Doi: 10.3390/vaccines10071134

Products & Services: Plasmid DNA Preparation

BioWF: A Naturally-Fused, Di-Domain Biocatalyst from Biotin Biosynthesis Displays an Unexpectedly Broad Substrate Scope

Authors: Shona M Richardson, Peter J Harrison, Michael A Herrera, Menglu Wang, Rebecca Verez, Gustavo Perez Ortiz, Dominic J Campopiano

Journal: Chembiochem

PubMed ID: 35695820

Doi: 10.1002/cbic.202200171

Products & Services: Plasmid DNA Preparation

A cell-free paper-based biosensor dependent on allosteric transcription factors (aTFs) for on-site detection of harmful metals Hg and Pb in water

Authors: Yongkang Zhang, Chen Zhao, Huaixiu Bi, Xi Zhang, Bin Xue, Chenyu Li, Shang Wang, Xiaobo Yang, Zhigang Qiu, Jingfeng Wang, Zhiqiang Shen