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Surface cysteine to serine substitutions in IL-18 reduce aggregation and enhance activity

Authors: Jirakrit Saetang, Niran Roongsawang, Surasak Sangkhathat, Supayang Piyawan Voravuthikunchai, Natnaree Sangkaew, Napat Prompat, Teerapol Srichana, Varomyalin Tipmanee

Journal: PeerJ

PubMed ID: 35811828

Doi: 10.7717/peerj.13626

Products & Services: Plasmid DNA Preparation

Durability of the Neutralizing Antibody Response to mRNA Booster Vaccination Against SARS-CoV-2 BA2121 and BA4/5 Variants

Authors: Panke Qu, Julia N Faraone, John P Evans, Yi-Min Zheng, Claire Carlin, Gerard Lozanski, Linda J Saif, Eugene M Oltz, Richard J Gumina, Shan-Lu Liu

Journal: biorxiv

PubMed ID: 35898337

Doi: 10.1101/2022.07.21.501010

Products & Services: Plasmid DNA Preparation

Structures of the T cell potassium channel Kv13 with immunoglobulin modulators

Authors: Purushotham Selvakumar, Ana I Fernández-Mariño, Nandish Khanra, Changhao He, Alice J Paquette, Bing Wang, Ruiqi Huang, Vaughn V Smider, William J Rice, Kenton J Swartz, Joel R Meyerson

Journal: Nat Commun

PubMed ID: 35788586

Doi: 10.1038/s41467-022-31285-5

Products & Services: Plasmid DNA Preparation

miR-301b-5p and its target gene nfatc2ip regulate inflammatory responses in the liver of rainbow trout (Oncorhynchus mykiss) under high temperature stress

Authors: Tianqing Huang, Wei Gu, Enhui Liu, Bingqian Wang, Gaochao Wang, Fulin Dong, Fuyuan Guo, Wenlong Jiao, Yanchun Sun, Xiance Wang, Shanwei Li, Gefeng Xu

Journal: Ecotoxicol Environ Saf

PubMed ID: 35901591

Doi: 10.1016/j.ecoenv.2022.113915

Products & Services: Plasmid DNA Preparation

Phage Particles of Controlled Length and Genome for Targeted Glioblastoma Imaging and Therapeutic Delivery

Authors: Uyanga Tsedev, Ching-Wei Lin, Gaelen T Hess, Jann N Sarkaria, Fred C Lam, Angela M Belcher

Journal: ACS Nano

PubMed ID: 35830573

Doi: 10.1021/acsnano.1c08720

Products & Services: Plasmid DNA Preparation

Cholesterol Deprivation Drives DHEA Biosynthesis in Human Adrenals

Authors: Emanuele Pignatti, Emre Murat Altinkilic, Konstantin Bräutigam, Michael Grössl, Aurel Perren, Mihaela Zavolan, Christa E Flück

Journal: Endocrinology

PubMed ID: 35583599

Doi: 10.1210/endocr/bqac076

Products & Services: Plasmid DNA Preparation

Discovery of a First-in-Class Degrader for Nuclear Receptor Binding SET Domain Protein 2 (NSD2) and Ikaros/Aiolos

Authors: Fanye Meng, Chenxi Xu, Kwang-Su Park, H Ümit Kaniskan, Gang Greg Wang, Jian Jin

Journal: J Med Chem

PubMed ID: 35895319

Doi: 10.1021/acs.jmedchem.2c00807

Products & Services: Plasmid DNA Preparation

A Novel Cre/lox71-Based System for Inducible Expression of Recombinant Proteins and Genome Editing

Authors: Maxim Karagyaur, Daniyar Dyikanov, Pyotr Tyurin-Kuzmin, Stalik Dzhauari, Mariya Skryabina, Maksim Vigovskiy, Alexandra Primak, Natalia Kalinina, Vsevolod Tkachuk

Journal: Cells

PubMed ID: 35883584

Doi: 10.3390/cells11142141

Products & Services: Plasmid DNA Preparation

Apela gene therapy alleviates pulmonary hypertension in rats

Authors: Yuexin Hu, Liangli Jin, Yang Pan, Jue Zou, Zhi Wang

Journal: FASEB J

PubMed ID: 35747913

Doi: 10.1096/fj.202200266R

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Cryo-EM structure of the human Kv3.1 channel reveals gating control by the cytoplasmic T1 domain

Authors: Gamma Chi , Qiansheng Liang , Akshay Sridhar , John B Cowgill , Kasim Sader , Mazdak Radjainia , Pu Qian , Pablo Castro-Hartmann , Shayla Venkaya , Nanki Kaur Singh , Gavin McKinley , Alejandra Fernandez-Cid , Shubhashish M M Mukhopadhyay , Nicola A Burgess-Brown , Lucie Delemotte , Manuel Covarrubias , Katharina L Dürr

Journal: Nat Commun

PubMed ID: 35840580

Doi: 10.1038/s41467-022-29594-w

Products & Services: Plasmid DNA Preparation