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Design of protein-binding proteins from the target structure alone
Authors: Longxing Cao, Brian Coventry, Inna Goreshnik, Buwei Huang, William Sheffler, Joon Sung Park, Kevin M Jude, Iva Marković, Rameshwar U Kadam, Koen H G Verschueren, Kenneth Verstraete, Scott Thomas Russell Walsh, Nathaniel Bennett, Ashish Phal, Aerin Yang, Lisa Kozodoy, Michelle DeWitt, Lora Picton, Lauren Miller, Eva-Maria Strauch, Nicholas D DeBouver, Allison Pires, Asim K Bera, Samer Halabiya, Bradley Hammerson, Wei Yang, Steffen Bernard, Lance Stewart, Ian A Wilson, Hannele Ruohola-Baker, Joseph Schlessinger, Sangwon Lee, Savvas N Savvides, K Christopher Garcia, David Baker
Journal: Nature
PubMed ID: 35332283
Doi: 10.1038/s41586-022-04654-9
Products & Services: Plasmid DNA Preparation   
Regulator of Actin-Based Motility (RoaM) Downregulates Actin Tail Formation by Rickettsia rickettsii and Is Negatively Selected in Mammalian Cell Culture
Authors: Adam M Nock, Tina R Clark, Ted Hackstadt
Journal: MBio
PubMed ID: 35285700
Doi: 10.1128/mbio.00353-22
Products & Services: Gene Synthesis   
Invalidation of dieckol and 1,2,3,4,6-pentagalloylglucose (PGG) as SARS-CoV-2 main protease inhibitors and the discovery of PGG as a papain-like protease inhibitor
Authors: Haozhou Tan, Chunlong Ma, Jun Wang
Journal: Res Sq
PubMed ID: 35378761
Doi: 10.21203/rs.3.rs-1490282/v1
Products & Services: Codon Optimization   
Interleukin-19 Aggravates Pulmonary Fibrosis via Activating Fibroblast through TGF-/Smad Pathway
Authors: Yu Wang, Sibo Sun, Kai Wang, Mingjiong Zhang, Min Li, Yumin Zan, Qiqing Huang, Shuangshuang Wu, Weihong Zhao, Wei Xu, Jianqing Wu
Journal: Mediators Inflamm
PubMed ID: 35281428
Doi: 10.1155/2022/6755407
Products & Services: Gene Synthesis   
Erythroid differentiation in mouse erythroleukemia cells depends on Tmod3-mediated regulation of actin filament assembly into the erythroblast membrane skeleton
Authors: Arit Ghosh, Megan Coffin, Richard West, Velia M Fowler
Journal: FASEB J
PubMed ID: 35195928
Doi: 10.1096/fj.202101011R
Products & Services: Catalog Peptides   
Glycosite-deleted mRNA of SARS-CoV-2 spike protein as a broad-spectrum vaccine
Authors: Chung-Yi Wu, Cheng-Wei Cheng, Chih-Chuan Kung, Kuo-Shiang Liao, Jia-Tsrong Jan, Che Ma, Chi-Huey Wong
Journal: Proc Natl Acad Sci U S A
PubMed ID: 35149556
Doi: 10.1073/pnas.2119995119
Products & Services: Codon Optimization   
Superior antitumor immunotherapy efficacy of kynureninase modified CAR-T cells through targeting kynurenine metabolism
Authors: Quanjun Yang, Juan Hao, Mengyi Chi, Yaxian Wang, Bo Xin, Jinglu Huang, Jin Lu, Jie Li, Xipeng Sun, Chunyan Li, Yan Huo, Jianping Zhang, Yonglong Han, Cheng Guo
Journal: Oncoimmunology
PubMed ID: 35355679
Doi: 10.1080/2162402X.2022.2055703
Products & Services: Synthetic sgRNA and crRNA Service   
VU6036720: The First Potent and Selective In Vitro Inhibitor of Heteromeric Kir41/51 Inward Rectifier Potassium Channels
Authors: Samantha J McClenahan, Caitlin N Kent, Sujay V Kharade, Elena Isaeva, Jade C Williams, Changho Han, Andrew Terker, Robert Gresham, Roman M Lazarenko, Emily L Days, Ian M Romaine, Joshua A Bauer, Olivier Boutaud, Gary A Sulikowski, Raymond Harris, C David Weaver, Alexander Staruschenko, Craig W Lindsley, Jerod S Denton
Journal: Mol Pharmacol
PubMed ID: 35246480
Doi: 10.1124/molpharm.121.000464
Products & Services: Gene Synthesis   
Atomic resolution dynamics of cohesive interactions in phase-separated Nup98 FG domains
Authors: Eszter E Najbauer, Sheung Chun Ng, Christian Griesinger, Dirk Görlich, Loren B Andreas
Journal: Nat Commun
PubMed ID: 35314668
Doi: 10.1038/s41467-022-28821-8
Products & Services: GenParts™ DNA Fragments   
Bmi-1 directly upregulates glucose transporter 1 in human gastric adenocarcinoma
Authors: Ying Guo, Guangyu Zhou, Qingjie Ma, Li Zhang, Jiwei Chen
Journal: Open Life Sci
PubMed ID: 35415241
Doi: 10.1515/biol-2022-0024
Products & Services: Gene Synthesis   
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