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Conserved allosteric inhibitory site on the respiratory syncytial virus and human metapneumovirus RNA-dependent RNA polymerases

Authors: Victoria A Kleiner, Thierry O Fischmann, John A Howe, Douglas C Beshore, Michael J Eddins, Yan Hou, Todd Mayhood, Daniel Klein, Debbie D Nahas, Bob J Lucas, He Xi, Edward Murray, Daphne Y Ma, Krista Getty, Rachel Fearns

Journal: Commun Biol

PubMed ID: 37337079

Doi: 10.1038/s42003-023-04990-0

Products & Services: Codon Optimization

Near atmospheric carbon dioxide activates plant ubiquitin cross-linking

Authors: Harry G Gannon, Martin J Cann

Journal: BBA Adv

PubMed ID: 37416898

Doi: 10.1016/j.bbadva.2023.100096

Products & Services: Molecular Biology Reagents

A bioengineered pseudovirus nanoparticle displaying SARS-CoV 2 RBD fully protects mice from mortality and weight loss caused by SARS-CoV 2 challenge

Authors: Ming Xia, Krisangel López, Frank S Vago, Pengwei Huang, Dawn I Auguste, Wen Jiang, Albert J Auguste, Ming Tan

Journal: Biotechnol J

PubMed ID: 37300425

Doi: 10.1002/biot.202300130

Products & Services: Molecular Biology Reagents

Assessing the Feasibility of Employing a Combination of a Bacteriophage-Derived Endolysin and Spore Germinants to Treat Relapsing Infection

Authors: Khalid Alyahya, Les Baillie

Journal: Microorganisms

PubMed ID: 37512824

Doi: 10.3390/microorganisms11071651

Products & Services: Custom Vector Construction

Expression and characterization of recombinant IL-1Ra in Aspergillus oryzae as a system

Authors: Lena Mahmoudi Azar, Elif Karaman, Burcu Beyaz, Işılay Göktan, Alp Ertunga Eyüpoğlu, Seda Kizilel, Batu Erman, Ahmet Gül, Serdar Uysal

Journal: BMC Biotechnol

PubMed ID: 37340430

Doi: 10.1186/s12896-023-00785-7

Products & Services: Gene Synthesis

Identification of paeoniflorin from Paeonia lactiflora pall As an inhibitor of tryptophan 2,3-dioxygenase and assessment of its pharmacological effects on depressive mice

Authors: Xiaoxia Liang, Ting Su, Pingzhou Wu, Yanting Dai, Yanmin Chen, QiQi Wang, Cheng Cao, Fenglian Chen, Qing Wang, Shuling Wang

Journal: J Ethnopharmacol

PubMed ID: 37315645

Doi: 10.1016/j.jep.2023.116714

Products & Services: Proteins, Expression, Isolation and Analysis

Antibody aggregation can lead to reduced Protein A binding capacity and low step yield

Authors: Gaoya Yuan, Meng Qu, Qi Geng, Wanyuan Dong, Xudong Zhang, Yifeng Li

Journal: Protein Expr Purif

PubMed ID: 37271409

Doi: 10.1016/j.pep.2023.106315

Products & Services: Proteins, Expression, Isolation and Analysis

Targeted deprivation of methionine with engineered Salmonella leads to oncolysis and suppression of metastasis in broad types of animal tumor models

Authors: Sujin Zhou, Yan Lin, Zhenggang Zhao, Yunhao Lai, Mengmeng Lu, Zishen Shao, Xinyu Mo, Yunping Mu, Zhipeng Liang, Xinxing Wang, Jingming Qu, Hua Shen, Fanghong Li, Allan Z Zhao

Journal: Cell Rep Med

PubMed ID: 37269826

Doi: 10.1016/j.xcrm.2023.101070

Products & Services: Custom Vector Construction

Effect of moderate prenatal ethanol exposure on the differential expression of two histamine H3 receptor isoforms in different brain regions of adult rat offspring

Authors: Suzy Davies, Kiana S Lujan, Ella J Rappaport, Carlos F Valenzuela, Daniel D Savage

Journal: Front Neurosci

PubMed ID: 37449267

Doi: 10.3389/fnins.2023.1192096

Products & Services: Proteins, Expression, Isolation and Analysis

Multisite transformation in : insights on transformations mechanisms and new genetic modification protocols

Authors: Vui Yin Seow, Olga Tsygelnytska, Nicolas Biais