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PAR4 Inhibition Reduces Coronary Artery Atherosclerosis and Myocardial Fibrosis in SR-B1/LDLR Double Knockout Mice

Authors: Samuel K Lee, Rida A Malik, Ji Zhou, Wei Wang, Peter L Gross, Jeffrey I Weitz, Rithwik Ramachandran, Bernardo L Trigatti

Journal: Arterioscler Thromb Vasc Biol

PubMed ID: 37675637

Doi: 10.1161/ATVBAHA.123.319767

Products & Services: Molecular Biology Reagents

Nanopore sequencing of DNA-barcoded probes for highly multiplexed detection of microRNA, proteins and small biomarkers

Authors: Caroline Koch, Benedict Reilly-O'Donnell, Richard Gutierrez, Carla Lucarelli, Fu Siong Ng, Julia Gorelik, Aleksandar P Ivanov, Joshua B Edel

Journal: Nat Nanotechnol

PubMed ID: 37749222

Doi: 10.1038/s41565-023-01479-z

Products & Services: Peptide Synthesis

CRISPR-ChIP reveals selective regulation of H3K79me2 by Menin in MLL leukemia

Authors: Omer Gilan, Laure Talarmain, Charles C Bell, Daniel Neville, Kathy Knezevic, Daniel T Ferguson, Marion Boudes, Yih-Chih Chan, Chen Davidovich, Enid Y N Lam, Mark A Dawson

Journal: Nat Struct Mol Biol

PubMed ID: 37679565

Doi: 10.1038/s41594-023-01087-4

Products & Services: Proteins, Expression, Isolation and Analysis

Differential regulatory control of curli (csg) gene expression in Salmonella enterica serovar Typhi requires more than a functional CsgD regulator

Authors: Camille Ou, Charles M Dozois, France Daigle

Journal: Sci Rep

PubMed ID: 37689734

Doi: 10.1038/s41598-023-42027-y

Products & Services: Monoclonal Antibody Services

Discovery of First-in-Class PROTAC Degraders of SARS-CoV-2 Main Protease

Authors: Yugendar R Alugubelli, Jing Xiao, Kaustav Khatua, Sathish Kumar, Yuying Ma, Xinyu R Ma, Veerabhadra R Vulupala, Sandeep R Atla, Lauren Blankenship, Demonta Coleman, Benjamin W Neuman, Wenshe Ray Liu, Shiqing Xu

Journal: biorxiv

PubMed ID: 37808777

Doi: 10.1101/2023.09.29.560163

Products & Services: Proteins, Expression, Isolation and Analysis

mRNA vaccines encoding fusion proteins of monkeypox virus antigens protect mice from vaccinia virus challenge

Authors: Fujun Hou, Yuntao Zhang, Xiaohu Liu, Yanal M Murad, Jiang Xu, Zhibin Yu, Xianwu Hua, Yingying Song, Jun Ding, Hongwei Huang, Ronghua Zhao, William Jia, Xiaoming Yang

Journal: Nat Commun

PubMed ID: 37739969

Doi: 10.1038/s41467-023-41628-5

Products & Services: Codon Optimization

A Proteorhodopsin-Related Photosensor Expands the Repertoire of Structural Motifs Employed by Sensory Rhodopsins

Authors: Maryam Saliminasab, Yoichi Yamazaki, Alyssa Palmateer, Andrew Harris, Luiz Schubert, Pit Langner, Joachim Heberle, Ana-Nicoleta Bondar, Leonid S Brown

Journal: J Phys Chem B

PubMed ID: 37694950

Doi: 10.1021/acs.jpcb.3c04032

Products & Services: Mutant Libraries Mutagenesis Services Gene Synthesis

Antibacterial Fusobacterium nucleatum-Mimicking Nanomedicine to Selectively Eliminate Tumor-Colonized Bacteria and Enhance Immunotherapy Against Colorectal Cancer

Authors: Linfu Chen , Rui Zhao , Jingjing Shen , Nanhui Liu , Zixuan Zheng , Yu Miao , Jiafei Zhu , Lin Zhang , Yingyao Wang , Huapan Fang , Jun Zhou , Maoyi Li , Yang Yang , Zhuang Liu , Qian Chen

Journal: Adv Mater .

PubMed ID: 37722134

Doi: 10.1002/adma.202306281

Products & Services: Gene Synthesis

TgLaforin, a glucan phosphatase, reveals the dynamic role of storage polysaccharides in tachyzoites and bradyzoites

Authors: Robert D Murphy, Cortni A Troublefield, Joy S Miracle, Lyndsay E A Young, Corey O Brizzee, Animesh Dhara, Ramon C Sun, Craig W Vander Kooi, Matthew S Gentry, Anthony P Sinai

Journal: biorxiv

PubMed ID: 37808860

Doi: 10.1101/2023.09.29.560185

Products & Services: Proteins, Expression, Isolation and Analysis

Enhancing CAR T-cell Therapy Using Fab-Based Constitutively Heterodimeric Cytokine Receptors

Authors: Matteo Righi, Isaac Gannon, Matthew Robson, Saket Srivastava, Evangelia Kokalaki, Thomas Grothier, Francesco Nannini, Christopher Allen, Yuchen V Bai, James Sillibourne, Shaun Cordoba, Simon Thomas, Martin Pule

Journal: Cancer Immunol Res

PubMed ID: 37352396

Doi: 10.1158/2326-6066.CIR-22-0640

Products & Services: Proteins, Expression, Isolation and Analysis