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Estrogen-mediated DNMT1 and DNMT3A recruitment by EZH2 silences miR-570-3p that contributes to papillary thyroid malignancy through DPP4

Authors: Xiarong Hu, Qingyao Ye, HuanQuan Lu, Zhiming Wu, Siyuan Chen, Ruinian Zheng

Journal: Clin Epigenetics

PubMed ID: 38890707

Doi: 10.1186/s13148-024-01685-z

Products & Services: Proteins, Expression, Isolation and Analysis

Enhanced Recombinant Protein Expression in Insect Cells by Natural and Recombinant Components of Lepidoptera Hemolymph

Authors: Javier López-Vidal, Susana Martínez-Pulgarín, Diego Martínez-Alonso, Miguel Cid, José M Escribano

Journal: Viruses

PubMed ID: 38932236

Doi: 10.3390/v16060944

Products & Services: Proteins, Expression, Isolation and Analysis

A quadrivalent recombinant influenza Hemagglutinin vaccine induced strong protective immune responses in animal models

Authors: Jin Feng, Yingying Du, Liyun Chen, Wenhan Su, Hailiu Wei, Aijiao Liu, Xiaojun Jiang, Jianmin Guo, Cailing Dai, Yuhua Xu, Tao Peng

Journal: Vaccine

PubMed ID: 38834431

Doi: 10.1016/j.vaccine.2024.05.056

Products & Services: Proteins, Expression, Isolation and Analysis Peptide Library Services

Intein-mediated temperature control for complete biosynthesis of sanguinarine and its halogenated derivatives in yeast

Authors: Yuanwei Gou, Dongfang Li, Minghui Zhao, Mengxin Li, Jiaojiao Zhang, Yilian Zhou, Feng Xiao, Gaofei Liu, Haote Ding, Chenfan Sun, Cuifang Ye, Chang Dong, Jucan Gao, Di Gao, Zehua Bao, Lei Huang, Zhinan Xu, Jiazhang Lian

Journal: Nat Commun

PubMed ID: 38898098

Doi: 10.1038/s41467-024-49554-w

Products & Services: Gene Synthesis

Protein engineering enables a soakable crystal form of human CDK7 primed for high-throughput crystallography and structure-based drug design

Authors: Manjeet Mukherjee, Philip J Day, Duncan Laverty, Juan A Bueren-Calabuig, Andrew J Woodhead, Charlotte Griffiths-Jones, Steve Hiscock, Charlotte East, Susan Boyd, Marc O'Reilly

Journal: Structure

PubMed ID: 38870939

Doi: 10.1016/j.str.2024.05.011

Products & Services: Custom Vector Construction

Dual-Omics Approach Unveils Novel Perspective on the Quality Control of Genetically Engineered Exosomes

Authors: Christopher Olson, Konstantin Ivanov, Darin Boyes, David Bengford, Joy Ku, Renceh Flojo, Pengyang Zhang, Biao Lu

Journal: Pharmaceutics

PubMed ID: 38931944

Doi: 10.3390/pharmaceutics16060824

Products & Services: Molecular Biology Reagents

Integrated pathway mining and selection of an artificial CYP79-mediated bypass to improve benzylisoquinoline alkaloid biosynthesis

Authors: Musashi Takenaka, Kouhei Kamasaka, Kim Daryong, Keiko Tsuchikane, Seiha Miyazawa, Saeko Fujihana, Yoshimi Hori, Christopher J Vavricka, Akira Hosoyama, Hiroko Kawasaki, Tomokazu Shirai, Michihiro Araki, Akira Nakagawa, Hiromichi Minami, Akihiko Kondo, Tomohisa Hasunuma

Journal: Microb Cell Fact

PubMed ID: 38879464

Doi: 10.1186/s12934-024-02453-7

Products & Services: Gene Synthesis

Designing monomeric IFNγ: the significance of domain-swapped dimer structure in IFNγ immune responses

Authors: Yota Goto, Takamitsu Miyafusa, Shinya Honda

Journal: J Biol Chem

PubMed ID: 38879015

Doi: 10.1016/j.jbc.2024.107464

Products & Services: Molecular Biology Reagents

Identification of potential crucial cuproptosis-related genes in myocardial ischemia-reperfusion injury through the bioinformatic analysis

Authors: Rong Huang, Rongfeng Xu, Rui Zhang, Wenjie Zuo, Zhenjun Ji, Zaixiao Tao, Yongjun Li, Genshan Ma