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Molecular cloning and in silico analysis of chalcone isomerase from Polygonum minus

Authors: Fatin Lyana Azman Shah, Syarul Nataqain Baharum, Hoe-Han Goh, Thean Chor Leow, Ahmad Bazli Ramzi, Siti Nurbaya Oslan, Suriana Sabri

Journal: Mol Biol Rep

PubMed ID: 37148413

Doi: 10.1007/s11033-023-08417-1

Products & Services: Recombinant Proteins

Structural basis for pre-tRNA recognition and processing by the human tRNA splicing endonuclease complex

Authors: Cassandra K Hayne, Kevin John U Butay, Zachary D Stewart, Juno M Krahn, Lalith Perera, Jason G Williams, Robert M Petrovitch, Leesa J Deterding, A Gregory Matera, Mario J Borgnia, Robin E Stanley

Journal: Nat Struct Mol Biol

PubMed ID: 37231153

Doi: 10.1038/s41594-023-00991-z

Products & Services: Gene Synthesis

GNAQ-Regulated ZO-1 and ZO-2 Act as Tumor Suppressors by Modulating EMT Potential and Tumor-Repressive Microenvironment in Lung Cancer

Authors: Hyung Seok Kim, Su In Lee, Yu Rim Choi, Jiyun Kim, Jung Woo Eun, Kyoung Seob Song, Jee-Yeong Jeong

Journal: Int J Mol Sci

PubMed ID: 37240145

Doi: 10.3390/ijms24108801

Products & Services: Recombinant Proteins

FOSL2 promotes intertumoral infiltration of T cells and increases pathological complete response rates in locally advanced rectal cancer patients

Authors: Kailun Xu, Xiaoyang Yin, Biting Zhou, Xi Zheng, Hao Wang, Jing Chen, Xue Cai, Huanhuan Gao, Xiaoming Xu, Liuhong Wang, Li Shen, Tiannan Guo, Shu Zheng, Baosheng Li, Yingkuan Shao, Jian Wang

Journal: CANCER LETTERS

PubMed ID: 36997107

Doi: 10.1016/j.canlet.2023.216145

Products & Services: Synthetic sgRNA and crRNA Service

Co-delivery of Cas9 mRNA and guide RNAs edits hepatitis B virus episomal and integration DNA in mouse and tree shrew models

Authors: Junzhu Yi, Xinlin Lei, Fangteng Guo, Qiubing Chen, Xueyong Chen, Kaitao Zhao, Chengliang Zhu, Xiaoming Cheng, Jiangwei Lin, Hao Yin, Yuchen Xia

Journal: Antiviral research

PubMed ID: 37142191

Doi: 10.1016/j.antiviral.2023.105618

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

Functionalized Metal–Organic Framework-Modified Hydrogel That Breaks the Vicious Cycle of Inflammation and ROS for Repairing of Diabetic Bone Defects

Authors: An Lao, Jiaqing Wu, Dejian Li, Aili Shen, Yaxin Li, Yu Zhuang, Kaili Lin, Jianyong Wu, Jiaqiang Liu

Journal: Small

PubMed ID: 37183293

Doi: smll.202206919

Products & Services: Proteins, Expression, Isolation and Analysis

Immunogenic SARS-CoV-2 S and N Protein Peptide and Cytokine Combinations as Biomarkers for Early Prediction of Fatal COVID-19

Authors: Ekaterina Martynova , Shaimaa Hamza , Maria Markelova , Ekaterina Garanina , Yuriy Davidyuk , Venera Shakirova , Neha Kaushal , Manoj Baranwal , Robert J Stott-Marshall , Toshana L Foster , Albert Rizvanov , Svetlana Khaiboullina

Journal: Front Immunol .

PubMed ID: 35386707

Doi: 10.3389/fimmu.2022.830715

Products & Services: Peptide Synthesis

In vitro reconstitution of SARS-CoV-2 Nsp1-induced mRNA cleavage reveals the key roles of the N-terminal domain of Nsp1 and the RRM domain of eIF3g

Authors: Irina S. Abaeva, Yani Arhab, Anna Miscicka, Christopher U.T. Hellen, and Tatyana V. Pestova

Journal: bioRxiv .

PubMed ID: 37292671

Doi: 10.1101/gad.350829.123

Products & Services: Gene Synthesis

Topically Administered NOX4 Inhibitor, GLX7013114, Is Efficacious in Treating the Early Pathological Events of Diabetic Retinopathy

Authors: Stavroula Dionysopoulou, Per Wikstrom, Claudio Bucolo, Giovanni Luca Romano, Vincenzo Micale, Richard Svensson, Dimitris Spyridakos, Niki Mastrodimou, Spiros Georgakis, Panayotis Verginis, Erik Walum, Kyriaki Thermos

Journal: Diabetes

PubMed ID: 36821829

Doi: 10.2337/db22-0515

Products & Services: Proteins, Expression, Isolation and Analysis

The Nucleocapsid Proteins of SARS-CoV-2 and Its Close Relative Bat Coronavirus RaTG13 Are Capable of Inhibiting PKR- and RNase L-Mediated Antiviral Pathways

Authors: Kyle LeBlanc, Jessie Lynch, Christine Layne, Robert Vendramelli, Angela Sloan, Nikesh Tailor, Yvon Deschambault, Fushun Zhang, Darwyn Kobasa, David Safronetz, Yan Xiang, Jingxin Cao

Journal: Microbiol Spectr

PubMed ID: 37154717

Doi: 10.1128/spectrum.00994-23

Products & Services: Proteins, Expression, Isolation and Analysis