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Environment relevant exposure of perfluorooctanoic acid accelerates the growth of hepatocellular carcinoma cells through mammalian target of rapamycin (mTOR) signal pathway

Authors: Jiawei Hong, Xiaoyan Wang, Hangbiao Jin, Yuanchen Chen, Yifan Jiang, Keyi Du, Diyu Chen, Shusen Zheng, Linping Cao

Journal: Environ Pollut

PubMed ID: 37967710

Doi: 10.1016/j.envpol.2023.122910

Products & Services: Proteins, Expression, Isolation and Analysis

Cationic ribosomal proteins can inhibit pro-inflammatory action stimulated by LPS+HMGB1 and are hindered by advanced glycation end products

Authors: Masahiro Watanabe, Takao Toyomura, Hidenori Wake, Takashi Nishinaka, Omer Faruk Hatipoglu, Hideo Takahashi, Masahiro Nishibori, Shuji Mori

Journal: Biotechnol Appl Biochem

PubMed ID: 38010900

Doi: 10.1002/bab.2538

Products & Services: Molecular Biology Reagents

Molecular basis for the catalytic mechanism of human neutral sphingomyelinases 1 (hSMPD2)

Authors: Jingbo Yi, Boya Qi, Jian Yin, Ruochong Li, Xudong Chen, Junhan Hu, Guohui Li, Sensen Zhang, Yuebin Zhang, Maojun Yang

Journal: Nat Commun

PubMed ID: 38012235

Doi: 10.1038/s41467-023-43580-w

Products & Services: Proteins, Expression, Isolation and Analysis

Extracellular and intracellular destruction of Pseudomonas aeruginosa by Dictyostelium discoideum phagocytes mobilize different antibacterial mechanisms

Authors: Imen Ayadi, Otmane Lamrabet, Raphael Munoz-Ruiz, Tania Jauslin, Cyril Guilhen, Pierre Cosson

Journal: Mol Microbiol

PubMed ID: 38017607

Doi: 10.1111/mmi.15197

Products & Services: Proteins, Expression, Isolation and Analysis

Phages overcome bacterial immunity via diverse anti-defence proteins

Authors: Erez Yirmiya, Azita Leavitt, Allen Lu, Adelyn E Ragucci, Carmel Avraham, Ilya Osterman, Jeremy Garb, Sadie P Antine, Sarah E Mooney, Samuel J Hobbs, Philip J Kranzusch, Gil Amitai, Rotem Sorek

Journal: Nature

PubMed ID: 37992756

Doi: 10.1038/s41586-023-06869-w

Products & Services: Gene Synthesis

Critical role of TPRN rings in the stereocilia for hearing

Authors: Jieyu Qi, Fangzhi Tan, Liyan Zhang, Yinyi Zhou, Ziyu Zhang, Qiuhan Sun, Nianci Li, Yuan Fang, Xin Chen, Yunhao Wu, Guisheng Zhong, Renjie Chai

Journal: Mol Ther

PubMed ID: 37952086

Doi: 10.1016/j.ymthe.2023.11.011

Products & Services: Proteins, Expression, Isolation and Analysis

DNAJB6 mutants display toxic gain of function through unregulated interaction with Hsp70 chaperones

Authors: Meital Abayev-Avraham, Yehuda Salzberg, Dar Gliksberg, Meital Oren-Suissa, Rina Rosenzweig

Journal: Nat Commun

PubMed ID: 37923706

Doi: 10.1038/s41467-023-42735-z

Products & Services: Proteins, Expression, Isolation and Analysis

Rational immunosilencing of a promiscuous T-cell epitope in the capsid of an adeno-associated virus

Authors: So Jin Bing, Morten Seirup, Trish T Hoang, Susana S Najera, Collin Britten, Stephanee L Warrington, Shiang-Ling Chu, Ronit Mazor

Journal: Nat Biomed Eng

PubMed ID: 37996615

Doi: 10.1038/s41551-023-01129-8

Products & Services: Peptide Synthesis

Regulated secretion of mutant p53 negatively affects T lymphocytes in the tumor microenvironment

Authors: Xiang Dong, Chunlu Li, Chengsi Deng, Jingwei Liu, Danni Li, Tingting Zhou, Xindi Yang, Yunchan Liu, Qiqiang Guo, Yanling Feng, Yang Yu, Zhuo Wang, Wendong Guo, Siyi Zhang, Hongyan Cui, Cui Jiang, Xiwen Wang, Xiaoyu Song, Xun Sun, Liu Cao

Journal: Oncogene

PubMed ID: 37952080

Doi: 10.1038/s41388-023-02886-1

Products & Services: Proteins, Expression, Isolation and Analysis

A novel ultrasensitive assay for plasma p-tau217: Performance in individuals with subjective cognitive decline and early Alzheimer's disease

Authors: Fernando Gonzalez-Ortiz, Pamela C L Ferreira, Armand González-Escalante, Laia Montoliu-Gaya, Paula Ortiz-Romero, Przemyslaw R Kac, Michael Turton, Hlin Kvartsberg, Nicholas J Ashton, Henrik Zetterberg, Peter Harrison, Bruna Bellaver, Guilherme Povala, Victor L Villemagne, Tharick A Pascoal, Mary Ganguli, Anne D Cohen, Carolina Minguillon, Jose Contador, Marc Suárez-Calvet, Thomas K Karikari, Kaj Blennow

Journal: Alzheimers Dement

PubMed ID: 37975513

Doi: 10.1002/alz.13525