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T-cell and antibody responses to first BNT162b2 vaccine dose in previously infected and SARS-CoV-2-naive UK health-care workers: a multicentre prospective cohort study
Authors: Adrienn Angyal, Stephanie Longet, Shona C Moore, Rebecca P Payne, Adam Harding, Tom Tipton, Patpong Rongkard, Mohammad Ali, Luisa M Hering, Naomi Meardon, James Austin, Rebecca Brown, Donal Skelly, Natalie Gillson, Sue L Dobson, Andrew Cross, Gurjinder Sandhar, Jonathan A Kilby, Jessica K Tyerman, Alexander R Nicols, Jarmila S Spegarova, Hema Mehta, Hailey Hornsby, Rachel Whitham, Christopher P Conlon, Katie Jeffery, Philip Goulder, John Frater, Christina Dold, Matthew Pace, Ane Ogbe, Helen Brown, M Azim Ansari, Emily Adland, Anthony Brown, Meera Chand, Adrian Shields, Philippa C Matthews, Susan Hopkins, Victoria Hall, William James, Sarah L Rowland-Jones, Paul Klenerman, Susanna Dunachie, Alex Richter, Christopher J A Duncan, Eleanor Barnes, Miles Carroll, Lance Turtle, Thushan I de Silva
Journal: Lancet Microbe
PubMed ID: 34778853
Doi: 10.1016/S2666-5247(21)00275-5
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Identification of immunogenic MHC class II human HER3 peptides that mediate anti-HER3 CD4+ Th1 responses and potential use as a cancer vaccine
Authors: Amrita Basu, Gabriella K Albert, Sabrina Awshah, Jashodeep Datta, Krithika N Kodumudi, Corey Gallen, Amber Beyer, Keiran S M Smalley, Paulo C Rodriguez, Derek R Dukett, Peter A Forsyth, Aixa Soyano, Gary K Koski, Ricardo Lima Barros Costa, Heather Han, Hatem Soliman, Marie Catherine Lee, Pawel Kalinski, Brian J Czerniecki
Journal: Cancer Immunol Res
PubMed ID: 34785506
Doi: 10.1158/2326-6066.CIR-21-0454
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Methodology to Quantify Collagen Subtypes and Crosslinks: Application in Minipig Cartilages
Authors: Benjamin J Bielajew, Jerry C Hu, Kyriacos A Athanasiou
Journal: Cartilage
PubMed ID: 34823380
Doi: 10.1177/19476035211060508
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Robust Antigen-Specific T Cell Activation within Injectable 3D Synthetic Nanovaccine Depots
Authors: Jorieke Weiden, Marjolein Schluck, Melina Ioannidis, Eric A W van Dinther, Mahboobeh Rezaeeyazdi, Fawad Omar, Juulke Steuten, Dion Voerman, Jurjen Tel, Mustafa Diken, Sidi A Bencherif, Carl G Figdor, Martijn Verdoes
Journal: ACS Biomater Sci Eng
PubMed ID: 34734689
Doi: 10.1021/acsbiomaterials.0c01648
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A class II MHC-targeted vaccine elicits immunity against SARS-CoV-2 and its variants
Authors: Novalia Pishesha, Thibault J Harmand, Paul W Rothlauf, Patrique Praest, Ryan K Alexander, Renate van den Doel, Mariel J Liebeskind, Maria A Vakaki, Nicholas McCaul, Charlotte Wijne, Elisha Verhaar, William Pinney, Hailey Heston, Louis-Marie Bloyet, Marjorie Cornejo Pontelli, Ma Xenia G Ilagan, Robert Jan Lebbink, William J Buchser, Emmanuel J H J Wiertz, Sean P J Whelan, Hidde L Ploegh
Journal: Proc Natl Acad Sci U S A
PubMed ID: 34654739
Doi: 10.1073/pnas.2116147118
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The barley HvSTP13GR mutant triggers resistance against biotrophic fungi
Authors: Caroline Ines Skoppek, Wilko Punt, Marleen Heinrichs, Frank Ordon, Gwendolin Wehner, Jens Boch, Jana Streubel
Journal: Mol Plant Pathol
PubMed ID: 34816582
Doi: 10.1111/mpp.13161
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CLAVATA3 mediated simultaneous control of transcriptional and post-translational processes provides robustness to the WUSCHEL gradient
Authors: Alexander Plong, Kevin Rodriguez, Mark Alber, Weitao Chen, G Venugopala Reddy
Journal: Nat Commun
PubMed ID: 34737298
Doi: 10.1038/s41467-021-26586-0
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Modified cyclodextrin-based nanoparticles mediated delivery of siRNA for huntingtin gene silencing across an in vitro BBB model
Authors: Monique C P Mendonça, Michael F Cronin, John F Cryan, Caitriona M O'Driscoll
Journal: Eur J Pharm Biopharm
PubMed ID: 34793942
Doi: 10.1016/j.ejpb.2021.11.003
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Quantitative contributions of TNF receptor superfamily members to CD8 T-cell responses
Authors: John Nguyen, Johannes Pettmann, Philipp Kruger, Omer Dushek
Journal: Mol Syst Biol
PubMed ID: 34806839
Doi: 10.15252/msb.202110560
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Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs
Authors: Mark Yarmarkovich, Quinlen F Marshall, John M Warrington, Rasika Premaratne, Alvin Farrel, David Groff, Wei Li, Moreno di Marco, Erin Runbeck, Hau Truong, Jugmohit S Toor, Sarvind Tripathi, Son Nguyen, Helena Shen, Tiffany Noel, Nicole L Church, Amber Weiner, Nathan Kendsersky, Dan Martinez, Rebecca Weisberg, Molly Christie, Laurence Eisenlohr, Kristopher R Bosse, Dimiter S Dimitrov, Stefan Stevanovic, Nikolaos G Sgourakis, Ben R Kiefel, John M Maris
Journal: Nature
PubMed ID: 34732890
Doi: 10.1038/s41586-021-04061-6
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