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A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
Authors: Coll RC, Robertson AA, Chae JJ, Higgins SC, Muñoz-Planillo R, Inserra MC, Vetter I, Dungan LS, Monks BG, Stutz A, Croker DE, Butler MS, Haneklaus M, Sutton CE, Núñez G, Latz E, Kastner DL, Mills KH, Masters SL, Schroder K, Cooper MA, O'Neill LA.
Journal: Nat Med
PubMed ID: 25686105
Doi: 10.1038/nm.3806
Products & Services: Peptide Synthesis   
Rational design of alpha-helical antimicrobial peptides: do's and don'ts
Authors: Uggerhøj LE, Poulsen TJ, Munk JK, Fredborg M, Sondergaard TE, Frimodt-Moller N, Hansen PR, Wimmer R.
Journal: Chembiochem
PubMed ID: 25530580
Doi: 10.1002/cbic.201402581
Products & Services: Peptide Synthesis   
Structure and host-receptor recognition studies of Gram-negative bacterial fimbriae assembled via the chaperone/usher pathway
Authors: Roy, Saumendra Prasad
Journal:  Department of Chemistry and Biotechnology (140101-161231)
Doi: 10.1111/mmi.12044
Products & Services: Peptide Synthesis   
Telephone-based goal management training for adults with mild traumatic brain injury: study protocol for a randomized controlled trial
Authors: Kristin R Archer, Rogelio A Coronado, Lori R Haislip, Christine M Abraham, Susan W Vanston, Anthony E Lazaro, James C Jackson, E Wesley Ely, Oscar D Guillamondegui, William T Obremskey
Journal: Trials
PubMed ID: 26031289
Doi: 10.1186/s13063-015-0775-1
Products & Services: Peptide Synthesis   
Real-time monitoring of viscosity changes triggered by chemical reactions using a high-speed imaging method.
Authors: Wooseok Jung, Cedric Hurth, Aimee Ellen Becker, Frederic Zenhausern.
Journal: Sensing and Bio-Sensing Research.
Products & Services: Peptide Synthesis   
The role of Notch signaling in muscle progenitor cell depletion and the rapid onset of histopathology in muscular dystrophy.
Authors: MuXiaodong,TangYing,LuAiping,TakayamaKoji,UsasArvydas,WangBing,WeissKurt,HuardJo
Journal: Hum. Mol. Genet.
PubMed ID: 25678553
Doi: 10.1093/hmg/ddv055
Products & Services: Peptide Synthesis   
Improved serological detection of rheumatoid arthritis: a highly antigenic mimotope of carbonic anhydrase III selected in a murine model by phage display.
Authors: AraujoGalber Rodrigues,VazEmília Rezende,FujimuraPatricia Tiemi,FonsecaJoão Eurico,de LimaLucélia Maria,CanhãoHelena,VenturiniGabriela,CardozoKarina Helena Morais,CarvalhoValdemir Melechco,NapimogaMarcelo Henrique,GoulartLuiz Ricardo,GonçalvesJoão,Ueira-VieiraCa
Journal: Arthritis Res. Ther.
PubMed ID: 26099944
Doi: 10.1186/s13075-015-0685-3
Products & Services: Peptide Synthesis   
A Homology Model Reveals Novel Structural Features and an Immunodominant Surface Loop/Opsonic Target in the Treponema pallidum BamA Ortholog TP_0326.
Authors: Luthra Amit,Anand Arvind,Hawley Kelly L,LeDoyt Morgan,La Vake Carson J,Caimano Melissa J,Cruz Adriana R,Salazar Juan C,Radolf Just
Journal: J. Bacteriol.
PubMed ID: 25825429
Doi: 10.1128/JB.00086-15
Products & Services: Peptide Synthesis   
Discovery of tricyclic indoles that potently inhibit Mcl-1 using fragment-based methods and structure-based design.
Authors: Burke Jason P,Bian Zhiguo,Shaw Subrata,Zhao Bin,Goodwin Craig M,Belmar Johannes,Browning Carrie F,Vigil Dominico,Friberg Anders,Camper DeMarco V,Rossanese Olivia W,Lee Taekyu,Olejniczak Edward T,Fesik Steph
Journal: J. Med. Chem.
PubMed ID: 25844895
Doi: 10.1021/jm501984f
Products & Services: Peptide Synthesis   
A conserved activation cluster is required for allosteric communication in HtrA-family proteases.
Authors: de Regt Anna K,Kim Seokhee,Sohn Jungsan,Grant Robert A,Baker Tania A,Sauer Robe
Journal: Structure
PubMed ID: 25703375
Doi: 10.1016/j.str.2015.01.012
Products & Services: Peptide Synthesis   
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