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Antibody binding of amyloid beta peptide epimers/isomers and ramifications for immunotherapies and drug development

Authors: Elizabeth R Readel, Arzoo Patel, Joshua I Putman, Siqi Du, Daniel W Armstrong

Journal: Sci Rep

PubMed ID: 37524807

Doi: 10.1038/s41598-023-38788-1

Products & Services: Peptide Synthesis

A conserved motif in the disordered linker of human MLH1 is vital for DNA mismatch repair and its function is diminished by a cancer family mutation

Authors: Karla Wolf, Jan Kosinski, Toby J Gibson, Nicole Wesch, Volker Dötsch, Maurizio Genuardi, Emanuela Lucci Cordisco, Stefan Zeuzem, Angela Brieger, Guido Plotz

Journal: Nucleic Acids Res

PubMed ID: 37224528

Doi: 10.1093/nar/gkad418

Products & Services: Peptide Synthesis

Cell targeting and immunostimulatory properties of a novel Fcγ-receptor-independent agonistic anti-CD40 antibody in rhesus macaques

Authors: Xianglei Yan, Sebastian Ols, Rodrigo Arcoverde Cerveira, Klara Lenart, Fredrika Hellgren, Kewei Ye, Alberto Cagigi, Marcus Buggert, Falk Nimmerjahn, Jesper Falkesgaard Højen, Daniel Parera, Ulrich Pessara, Stephan Fischer, Karin Loré

Journal: Cell Mol Life Sci

PubMed ID: 37353664

Doi: 10.1007/s00018-023-04828-2

Products & Services: Peptide Synthesis

Detection of phosphorylation post-translational modifications along single peptides with nanopores

Authors: Ian C Nova, Justas Ritmejeris, Henry Brinkerhoff, Theo J R Koenig, Jens H Gundlach, Cees Dekker

Journal: Nat Biotechnol

PubMed ID: 37386295

Doi: 10.1038/s41587-023-01839-z

Products & Services: Peptide Synthesis

Rise of the RNA machines - self-amplification in mRNA vaccine design

Authors: Jerome D G Comes, Gorben P Pijlman, Tessy A H Hick

Journal: Trends Biotechnol

PubMed ID: 37328401

Doi: 10.1016/j.tibtech.2023.05.007

Products & Services: Peptide Synthesis

N-terminal intrinsic disorder is an ancestral feature of Gγ subunits that influences the balance between different Gβγ signaling axes in yeast

Authors: Xinya Su, Yui Tik Pang, Wei Li, J C Gumbart, Joshua Kelley, Matthew Torres

Journal: J Biol Chem

PubMed ID: 37354971

Doi: 10.1016/j.jbc.2023.104947

Products & Services: Peptide Synthesis

Exploration of T cell immune responses by expression of a dominant-negative SHP1 and SHP2

Authors: Julia Taylor, Anna Bulek, Isaac Gannon, Mathew Robson, Evangelia Kokalaki, Thomas Grothier, Callum McKenzie, Mohamed El-Kholy, Maria Stavrou, Charlotte Traynor-White, Wen Chean Lim, Panagiota Panagiotou, Saket Srivastava, Vania Baldan, James Sillibourne, Mathieu Ferrari, Martin Pule, Simon Thomas

Journal: Front Immunol

PubMed ID: 37334382

Doi: 10.3389/fimmu.2023.1119350

Products & Services: Peptide Synthesis

Nullomer peptide increases immune cell infiltration and reduces tumor metabolism in triple negative breast cancer mouse model

Authors: Nilufar Ali, Cody Wolf, Swarna Kanchan, Shivakumar R Veerabhadraiah, Laura Bond, Matthew W Turner, Cheryl L Jorcyk, Greg Hampikian

Journal: Res Sq

PubMed ID: 37461536

Doi: 10.21203/rs.3.rs-3097552/v1

Products & Services: Peptide Synthesis

Identification of a damage-associated molecular pattern (DAMP) receptor and its cognate peptide ligand in sweet potato (Ipomoea batatas)

Authors: Hsueh-Han Lu, Anja K Meents, Judith Fliegmann, Ming-Jing Hwang, Ching-Shu Suen, Diana Masch, Georg Felix, Axel Mithöfer, Kai-Wun Yeh