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A broadly neutralizing antibody recognizes a unique epitope with a signature motif common across coronaviruses

Authors: Lei Yan, Fulian Wang, Michelle Hill, Juliane Brun, Ze Liang, Xinyu Shi, Liangminghui Zhang, Xiuxiu He, Yu Li, Qianping Huang, Xuxue Dong, Huanzhen Liu, Yi Zhang, Lili Liu, Raymond A Dwek, Nicole Zitzmann, Aibin Liang, Guang Yang

Journal: Nature Communications

PubMed ID: 40813592

Doi: doi.org/10.1038/s41467-025-63101-1

Products & Services: Peptide Synthesis

Functionalized Annealed Microgels for Spatial Control of Osteogenic and Chondrogenic Differentiation

Authors: Jeremy M. Lowen, Erika E. Wheeler, Nathan K. Shimamoto, David H. Ramos-Rodriguez, Katherine H. Griffin, Gabriella C. Bond, J. Kent Leach

Journal: ADVANCED FUNCTIONAL MATERIALS

Doi: 10.1002/adfm.202311017

Products & Services: Peptide Synthesis

Antimicrobial and Potent Anti- Biofilm Properties of Rationally Designed α- Helix Antimicrobial Peptides

Authors: Motasim Ismael, Khayeli Juliah, Madivoli Edwin

Journal: Journal of Peptide Science

PubMed ID: 40326595

Doi: 10.1002/psc.70027

Products & Services: Peptide Synthesis

Host protein ARF1 is a proviral factor for SARS-CoV-2 and a candidate broad-spectrum therapeutic target

Authors: Cunhuan Zhang, Yuan-Qin Min, Heng Xue, Haiyan Zhang, Kunpeng Liu, Yichao Tian, Ziying Yang, Zihan Zhao, Hang Yang, Chao Shan, Xiulian Sun & Yun-Jia Ning

Journal: Nature Communication

Doi: 10.1038/s41467-025-61431-8

Products & Services: Peptide Synthesis

LPS-enriched interaction drives spectrum conversion in antimicrobial peptides: Design and optimization of AA16 derivatives for targeting gram-negative bacteria

Authors: Wanyang Xiao, Ruize Sun, Jietao Lou, Yanyan Xu, Xiaokun Li, Kaiyun Xin, Weijie Lu, Chenhui Sun, Tianbao Chen, Yitian Gao, Di Wu

Journal: Eur J Med Chem

PubMed ID: 40048797

Doi: 10.1016/j.ejmech.2025.117462

Products & Services: Peptide Synthesis

Human skeletal development and regeneration are shaped by functional diversity of stem cells across skeletal sites

Authors: Thomas H Ambrosi, Sahar Taheri, Kun Chen, Rahul Sinha, Yuting Wang, Ethan J Hunt, L Henry Goodnough, Matthew P Murphy, Holly M Steininger, Malachia Y Hoover, Franco Felix, Kelly C Weldon, Lauren S Koepke, Jan Sokol, Daniel Dan Liu, Liming Zhao, Stephanie D Conley, Wan-Jin Lu, Maurizio Morri, Norma F Neff, Noelle L Van Rysselberghe, Erika E Wheeler, Yongheng Wang, J Kent Leach, Augustine Saiz, Aijun Wang, George P Yang, Stuart Goodman, Julius A Bishop, Michael J Gardner, Derrick C Wan, Irving L Weissman, Michael T Longaker, Debashis Sahoo, Charles K F Chan

Journal: Cell Stem Cell

PubMed ID: 40118065

Doi: 10.1016/j.stem.2025.02.013

Products & Services: Peptide Synthesis

N-Terminal random curl-tandam α-helical peptide 7W: A potent antibacterial and anti-inflammatory dual-effect agent through tryptophan substitution

Authors: Jietao Lou, Xinyi Wu, Wenwen Ji, Jiaye Yu, Yanyan Xu, Wanyang Xiao, Weijie Lu, Kaiyun Xin, Tianbao Chen, Qidong Tang, Guang Liang, Yitian Gao, Di Wu

Journal: Eur J Med Chem

PubMed ID: 40319576

Doi: 10.1016/j.ejmech.2025.117686

Products & Services: Peptide Synthesis

PIN1-SUMO2/3 motif suppresses excessive RNF168 chromatin accumulation and ubiquitin signaling to promote IR resistance

Authors: Anoop S Chauhan, Matthew J W Mackintosh, Joseph Cassar, Alexander J Lanz, Mohammed Jamshad, Hannah L Mackay, Alexander J Garvin, Alexandra K Walker, Satpal S Jhujh, Teresa Carlomagno, Aneika C Leney, Grant S Stewart, Joanna R Morris

Journal: Nature Communication

PubMed ID: 40229270

Doi: 10.1038/s41467-025-56974-9

Products & Services: Peptide Synthesis Monoclonal Antibody Services

Metabolite-dependent m6A methylation driven by mechanotransduction-metabolism-epitranscriptomics axis promotes bone development and regeneration

Authors: Zhuo Li, Zhengnan Guo, Zhengmeng Yang, Boguang Yang, Yuan Hu, Xian Xie, Zhixian Zong, Zekun Chen, Kunyu Zhang, Pengchao Zhao, Gang Li, Xuefeng Yang, Liming Bian

Journal: Cell Rep

PubMed ID: 40272981

Doi: 10.1016/j.celrep.2025.115611

Products & Services: Peptide Synthesis

Using Regular Porous Membrane-Based Blood−Brain Barrier Model to Screen Brain-Targeted Drugs with Nanochannel Electrochemistry

Authors: Yafeng Wu，Zixuan Chen，Fengxiang Chen，Juan Su，Jianyu Han，Songqin Liu

Journal: Anal Chem

PubMed ID: 40183921

Doi: 10.1021/acs.analchem.5c00365

Products & Services: Peptide Synthesis