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Antiviral activity of immunosuppressors alone and in combination against human adenovirus and cytomegalovirus

Authors: Marta Carretero-Ledesma, Manuela Aguilar-Guisado, Judith Berastegui-Cabrera, María Balsera-Manzanero, Jerónimo Pachón, Elisa Cordero, Javier Sánchez-Céspedes

Journal: Int J Antimicrob Agents

PubMed ID: 38401774

Doi: 10.1016/j.ijantimicag.2024.107116

Products & Services: PCR Cloning and Subcloning

Integrating network pharmacology and experimental models to identify notoginsenoside R1 ameliorates atherosclerosis by inhibiting macrophage NLRP3 inflammasome activation

Authors: Jingyue Yu, Jinyu Hu, Margaret Baldini, Huan Lei, Lei Li, Shanshan Luo, Jielian Wu, Xupin Liu, Dan Shan, Yanfei Xie, Haihong Fang, Jun Yu

Journal: J Nat Med

PubMed ID: 38409483

Doi: 10.1007/s11418-023-01776-w

Products & Services: PCR Cloning and Subcloning

Visualizing the impact of disease-associated mutations on G protein-nucleotide interactions

Authors: Kara Anazia, Lucien Koenekoop, Guillaume Ferré, Enzo Petracco, Hugo Gutiérrez-de-Teran, Matthew T Eddy

Journal: biorxiv

PubMed ID: 38352316

Doi: 10.1101/2024.01.30.578006

Products & Services: PCR Cloning and Subcloning

Expression of GPX4 by oncolytic vaccinia virus can significantly enhance CD8T cell function and its impact against pancreatic ductal adenocarcinoma

Authors: Wei Wei, Linqing Tian, Xiaoyan Zheng, Lei Zhong, Yuan Chen, Hui Dong, Guibing Zhang, Shibing Wang, Xiangmin Tong

Journal: Oncoimmunology

PubMed ID: 38419758

Doi: 10.1080/2162402X.2024.2322173

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Immune evasion, infectivity, and fusogenicity of SARS-CoV-2 BA. 2.86 and FLip variants

Authors: Panke Qu 1, Kai Xu 1, Julia N Faraone 2, Negin Goodarzi 1, Yi-Min Zheng 1, Claire Carlin 3, Joseph S Bednash 4, Jeffrey C Horowitz 4, Rama K Mallampalli 4, Linda J Saif 5, Eugene M Oltz 6, Daniel Jones 7, Richard J Gumina 8, Shan-Lu Liu

Journal: Cell

PubMed ID: 38194968

Doi: 10.1016/j.cell.2023.12.026

Products & Services: PCR Cloning and Subcloning

Functional analyses of TRAF6 gene in Argopecten scallops

Authors: Xiaotong Zhang, Xia Wang, Jieyu Chen, Min Chen, Xia Lu, Junhao Ning, Haijun Liu, Guilong Liu, Xin Xu, Xiaoxu Qu, Kai Yu, He Xu, Chunde Wang, Bo Liu

Journal: Fish Shellfish Immunol

PubMed ID: 38354964

Doi: 10.1016/j.fsi.2024.109443

Products & Services: PCR Cloning and Subcloning

N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting

Authors: Thomas E Mulroney, Tuija Pöyry, Juan Carlos Yam-Puc, Maria Rust, Robert F Harvey, Lajos Kalmar, Emily Horner, Lucy Booth, Alexander P Ferreira, Mark Stoneley, Ritwick Sawarkar, Alexander J Mentzer, Kathryn S Lilley, C Mark Smales, Tobias von der Haar, Lance Turtle, Susanna Dunachie, Paul Klenerman, James E D Thaventhiran, Anne E Willis

Journal: Nature

PubMed ID: 38057663

Doi: 10.1038/s41586-023-06800-3

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Enhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds

Authors: Eike-Christian Wamhoff , Larance Ronsard , Jared Feldman , Grant A Knappe , Blake M Hauser , Anna Romanov , James Brett Case , Shilpa Sanapala , Evan C Lam , Kerri J St Denis , Julie Boucau , Amy K Barczak , Alejandro B Balazs , Michael S Diamond , Aaron G Schmidt , Daniel Lingwood , Mark Bathe

Journal: Nat Commun

PubMed ID: 38291019

Doi: 10.1038/s41467-024-44869-0

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Single-Molecule Analysis of SARS-CoV-2 Double-Stranded Polynucleotides Using Solid-State Nanopore with AI-Assisted Detection and Classification: Implications for Understanding Disease Severity

Authors: Ibrar Alam, Thitikorn Boonkoom, Harit Pitakjakpipop, Poramin Boonbanjong, Kawin Loha, Thanaya Saeyang, Jarunee Vanichtanankul, Deanpen Japrung

Journal: ACS Appl Bio Mater

PubMed ID: 38194666

Doi: 10.1021/acsabm.3c00998

Products & Services: PCR Cloning and Subcloning

In situ vaccination via tissue-targeted cDC1 expansion enhances the immunogenicity of chemoradiation and immunotherapy

Authors: Brandon Lam, Yu Jui Kung, John Lin, Ssu-Hsueh Tseng, Hsin-Fang Tu, Claire Huang, Brandon Lee, Esteban Velarde, Ya Chea Tsai, Rafael Villasmil, Sung Taek Park, Deyin Xing, Chien-Fu Hung, T-C Wu

Journal: J Clin Invest

PubMed ID: 37917174

Doi: 10.1172/JCI171621

Products & Services: PCR Cloning and Subcloning