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Optimization of Potent and Specific Trypanothione Reductase Inhibitors: A Structure-Based Drug Discovery Approach

Authors: Theo Battista, Stefano Federico, Simone Brogi, Luca Pozzetti, Tuhina Khan, Stefania Butini, Anna Ramunno, Eleonora Fiorentino, Stefania Orsini, Trentina Di Muccio, Annarita Fiorillo, Cécile Exertier, Daniel Di Risola, Gianni Colotti, Sandra Gemma, Andrea Ilari, Giuseppe Campiani

Journal: ACS Infect Dis

PubMed ID: 35880849

Doi: 10.1021/acsinfecdis.2c00325

Products & Services: PCR Cloning and Subcloning

Protective Human Anti-Poxvirus Monoclonal Antibodies Are Generated from Rare Memory B Cells Isolated by Multicolor Antigen Tetramers

Authors: Xiuling Gu, Yufan Zhang, Wei Jiang, Dongfang Wang, Jiao Lu, Guanglei Gu, Chengfeng Qin, Min Fang

Journal: Vaccines (Basel)

PubMed ID: 35891248

Doi: 10.3390/vaccines10071084

Products & Services: PCR Cloning and Subcloning

Evaluation of residue variability in a conformation-specific context and during evolutionary sequence reconstruction narrows drug resistance selection in Abl1 tyrosine kinase

Authors: Felipe A M Otsuka, Sinisa Bjelic

Journal: Protein Sci

PubMed ID: 35762721

Doi: 10.1002/pro.4354

Products & Services: PCR Cloning and Subcloning

Free fatty acid receptor 4 deletion attenuates colitis by modulating Treg Cells via ZBED6-IL33 pathway.

Authors: Shenglong Zhu, Jingwei Zhang, Xuan Jiang, Wei Wang, Yong Q Chen

Journal: EBioMedicine

PubMed ID: 35588628

Doi: 10.1016/j.ebiom.2022.104060

Products & Services: PCR Cloning and Subcloning

Tomato brown rugose fruit virus resistance generated by quadruple knockout of homologs of TOBAMOVIRUS MULTIPLICATION1 in tomato

Authors: Masayuki Ishikawa, Tetsuya Yoshida, Momoko Matsuyama, Yusuke Kouzai, Akihito Kano, Kazuhiro Ishibashi

Journal: Plant Physiol

PubMed ID: 35262730

Doi: 10.1093/plphys/kiac103

Products & Services: PCR Cloning and Subcloning

Overproduction, Purification, and Stability of the Functionally Active Human Carnitine Acetyl Transferase

Authors: Deborah Giudice, Lara Console, Arduino Arduini, Cesare Indiveri

Journal: Mol Biotechnol

PubMed ID: 35727434

Doi: 10.1007/s12033-022-00522-z

Products & Services: PCR Cloning and Subcloning

Immunogenicity of SARS-CoV-2 Trimeric Spike Protein Associated to Poly(I:C) Plus Alum

Authors: Júlio Souza Dos-Santos, Luan Firmino-Cruz, Alessandra Marcia da Fonseca-Martins, Diogo Oliveira-Maciel, Gustavo Guadagnini Perez, Victor A Roncaglia-Pereira, Carlos H Dumard, Francisca H Guedes-da-Silva, Ana C Vicente Santos, Monique Dos Santos Leandro, Jesuino Rafael Machado Ferreira, Kamila Guimarães-Pinto, Luciana Conde, Danielle A S Rodrigues, Marcus Vinicius de Mattos Silva, Renata G F Alvim, Tulio M Lima, Federico F Marsili, Daniel P B Abreu, Orlando C Ferreira, Ronaldo da Silva Mohana Borges, Amilcar Tanuri, Thiago Moreno L Souza, Bartira Rossi-Bergmann, André M Vale, Jerson Lima Silva, Andréa Cheble de Oliveira, Alessandra D'Almeida Filardy, Andre M O Gomes, Herbert Leonel de Matos Guedes

Journal: Front Immunol

PubMed ID: 35844561

Doi: 10.3389/fimmu.2022.884760

Products & Services: PCR Cloning and Subcloning

Development of a biosensor based on a new marine luciferase fused to an affibody to assess Her2 expression in living cells

Authors: Laura Rodríguez de la Fuente, Irene Golán Cancela, Ánxela M Estévez-Salguero, Pablo Iglesias, José A Costoya

Journal: Anal Chim Acta

PubMed ID: 35934341

Doi: 10.1016/j.aca.2022.340084

Products & Services: PCR Cloning and Subcloning

Structural insights into the lysophospholipid brain uptake mechanism and its inhibition by syncytin-2

Authors: Maria Martinez-Molledo, Emmanuel Nji, Nicolas Reyes

Journal: Nat Struct Mol Biol

PubMed ID: 35710838

Doi: 10.1038/s41594-022-00786-8

Products & Services: PCR Cloning and Subcloning

Preclinical study of formulated recombinant nucleocapsid protein, the receptor binding domain of the spike protein, and truncated spike (S1) protein as vaccine candidates against COVID-19 in animal models

Authors: Shahram Nazarian, Gholamreza Olad, Raziyeh Abdolhamidi, Mohammad Javad Motamedi, Rouhollah Kazemi, Emad Kordbacheh, Alireza Felagari, Hanieh Olad, Ali Ahmadi, Alireza Bahiraee, Parisa Farahani, Leila Haghighi, Faezeh Hassani, Vahideh Hajhassan, Mona Nadi, Abdolkarim Sheikhi, Jafar Salimian, Jafar Amani

Journal: Mol Immunol

PubMed ID: 35802999

Doi: 10.1016/j.molimm.2022.06.007

Products & Services: PCR Cloning and Subcloning