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Intramuscular delivery of formulated RNA encoding six linked nanobodies is highly protective for exposures to three Botulinum neurotoxin serotypes

Authors: Jean Mukherjee, Celinia A Ondeck, Jacqueline M Tremblay, Jacob Archer, Michelle Debatis, Alexa Foss, Junya Awata, Jesse H Erasmus, Patrick M McNutt, Charles B Shoemaker

Journal: Sci Rep

PubMed ID: 35803998

Doi: 10.1038/s41598-022-15876-2

Products & Services: Gene Synthesis

Silencing lncRNA 93358 Inhibits the Apoptosis of Myocardial Cells in Myocardial Infarction Rats by Inducing the Expression of SLC8A1

Authors: Jiumei Cai, Xiaoping Wang, Wei Liao, Yiming Zhong, Lingling Chen, Zhiwei Zhang

Journal: Biomed Res Int

PubMed ID: 35845941

Doi: 10.1155/2022/1138709

Products & Services: Gene Synthesis

Polymeric nanoparticles for dual-targeted theranostic gene delivery to hepatocellular carcinoma

Authors: Hannah J Vaughan, Camila G Zamboni, Laboni F Hassan, Nicholas P Radant, Desmond Jacob, Ronnie C Mease, Il Minn, Stephany Y Tzeng, Kathleen L Gabrielson, Pranshu Bhardwaj, Xin Guo, David Francisco, Martin G Pomper, Jordan J Green

Journal: Sci Adv

PubMed ID: 35857843

Doi: 10.1126/sciadv.abo6406

Products & Services: Gene Synthesis

Self-Masked Aldehyde Inhibitors of Human Cathepsin L Are Potent Anti-CoV-2 Agents

Authors: Jiyun Zhu, Linfeng Li, Aleksandra Drelich, Bala C Chenna, Drake M Mellott, Zane W Taylor, Vivian Tat, Christopher Z Garcia, Ardala Katzfuss, Chien-Te K Tseng, Thomas D Meek

Journal: Front Chem

PubMed ID: 35860632

Doi: 10.3389/fchem.2022.867928

Products & Services: Gene Synthesis

Induction of Broadly Cross-Reactive Antibody Responses to SARS-CoV-2 Variants by S1 Nanoparticle Vaccines

Authors: Cong Sun , Run-Yu Yuan , Chu Xie , Jiu-Feng Sun , Xin-Yan Fang , Yi-Sha Hu , Xiao-Hui Yu, Zheng Liu , Mu-Sheng Zeng , Yin-Feng Kang

Journal: J Virol

PubMed ID: 35699445

Doi: 10.1128/jvi.00383-22

Products & Services: Gene Synthesis Endotoxin Detection & Removal System

A precise and efficient adenine base editor

Authors: Tianxiang Tu , Zongming Song , Xiaoyu Liu , Shengxing Wang , Xiaoxue He , Haitao Xi , Jiahua Wang , Tong Yan , Haoran Chen , Zhenwu Zhang , Xiujuan Lv , Jineng Lv , Xiu-Feng Huang , Junzhao Zhao , Chao-Po Lin , Caixia Gao , Jinwei Zhang , Feng Gu

Journal: Mol Ther

PubMed ID: 35821638

Doi: 10.1016/j.ymthe.2022.07.010

Products & Services: Gene Synthesis

Silencing the enhancer of zeste homologue 2, E, represses axon regeneration of dorsal root ganglion neuronszh 2

Authors: Ting-Ting Guo, Ying Zhao, Wei-Xiao Huang, Tao Zhang, Li-Li Zhao, Xiao-Song Gu, Song-Lin Zhou

Journal: Neural Regen Res

PubMed ID: 34916437

Doi: 10.4103/1673-5374.330623

Products & Services: Gene Synthesis

CAR T-Cell Targeting of Macrophage Colony-Stimulating Factor Receptor

Authors: Daniela Yordanova Achkova, Richard Esmond Beatson, John Maher

Journal: Cells

PubMed ID: 35883636

Doi: 10.3390/cells11142190

Products & Services: Gene Synthesis

Tryptophan C-mannosylation is critical for Plasmodium falciparum transmission

Authors: Sash Lopaticki, Robyn McConville, Alan John, Niall Geoghegan, Shihab Deen Mohamed, Lisa Verzier, Ryan W J Steel, Cindy Evelyn, Matthew T O'Neill, Niccolay Madiedo Soler, Nichollas E Scott, Kelly L Rogers, Ethan D Goddard-Borger, Justin A Boddey

Journal: Nat Commun

PubMed ID: 35906227

Doi: 10.1038/s41467-022-32076-8

Products & Services: Gene Synthesis

Structural insights into GABA transport inhibition using an engineered neurotransmitter transporter

Authors: Deepthi Joseph, Smruti Ranjan Nayak, Aravind Penmatsa

Journal: EMBO J

PubMed ID: 35796008

Doi: 10.15252/embj.2022110735

Products & Services: Gene Synthesis