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页码: 4/789 每页显示数量

Enhancing mRNA translation efficiency by introducing sequence optimized AU-rich elements in 3′ UTR via HuR anchorage

Authors: Xinghuan Ma , Sujia Liu , Bangda Fan , Danni Jin , Lei Miao , Lin Liu , Shubo Du , Jiaqi Lin

Journal: Mol Ther Nucleic Acids

PubMed ID: 40125272

Doi: doi.org/10.1016/j.omtn.2025.102485

Products & Services: Gene Synthesis

Controllable intein splicing and N-terminal cleavage at mesophilic temperatures

Authors: Taylor A McNeal, Joel Weinberger, Geraldy L S Liman, Tia M Ariagno, David W Wood, Thomas J Santangelo, Christopher W Lennon

Journal: Front Bioeng Biotechnol

PubMed ID: 39991137

Doi: 10.3389/fbioe.2025.1543573

Products & Services: Gene Synthesis Mutagenesis Services

Distinct immunogenicity outcomes of DNA vaccines encoding malaria transmission-blocking vaccine target antigens Pfs230D1M and Pvs230D1

Authors: Yi Cao , Maisa da Silva Araujo , Cynthia G Lorang , Najara Akira Costa Dos Santos , Abhai Tripathi , Joseph Vinetz , Nirbhay Kumar

Journal: Vaccine

PubMed ID: 39787798

Doi: 10.1016/j.vaccine.2024.126696

Products & Services: Gene Synthesis Plasmid DNA Preparation

Elastin-like polypeptide: A novel titanification biomacromolecule for green and ultrafast synthesis of biotitania nanoparticles via biomimetic mineralization

Authors: Lixi Cai, Jinlin Zheng, Lixing Liu, Guangya Zhang, Yuanqing Lin

Journal: Int J Biol Macromol

PubMed ID: 40015400

Doi: 10.1016/j.ijbiomac.2025.141449

Products & Services: Gene Synthesis

A Granzyme B‑Cleavable T Cell-Targeted Bispecific Cell Vesicle Connector for Reversing New-Onset Type 1 Diabetes

Authors: Yanfang Wang, Yanping Sun, Xiuwen Zhang, Shenqiang Wang, Xuehui Huang, Kairui Xu, Yun Liu, Yingqi Huang, Jianchang Xu, Xinwei Wei, Hao Cheng, Liqiang Pan, Jinqiang Wang, Zhen Gu

Journal: Journal of the American Chemical Society

PubMed ID: 39869523

Doi: 10.1021/jacs.4c13644

Products & Services: Gene Synthesis

Tailorable biosensors for real-time monitoring of stress distribution in soft biomaterials and living tissues

Authors: Fenghou Yuan, Huitang Qi, Binghui Song, Yuntian Cui, Junsheng Zhang, Huan Liu, Bo Liu, Hai Lei, Tian Liu

Journal: nature COMMUNICATION

PubMed ID: 39870637

Doi: doi.org/10.1038/s41467-025-56422-8

Products & Services: Gene Synthesis

A nanobody-enzyme fusion protein targeting PD-L1 and sialic acid exerts anti-tumor effects by C-type lectin pathway-mediated tumor associated macrophages repolarizing

Authors: Yongliang Tong , Runqiu Chen , Xinrong Lu , Cuiying Chen , Guiqin Sun , Xiaolu Yu , Shaoxian Lyu , Meiqing Feng , Yiru Long , Likun Gong , Li Chen

Journal: Int J Biol Macromol

PubMed ID: 39824395

Doi: 10.1016/j.ijbiomac.2025.139953

Products & Services: Gene Synthesis

Restoring tumor antigenicity activates the “bystander” T cell immune cycle

Authors: Yifan Yang , Qiumin Yu , Haoyu Zhang , Yuchen Liu , Hexuan Wang , Ningyi Yang , Yulian Shi , Wanli Zhang , Zijie Wu , Shitong Huang , Wenbin Xie , Ran Duan , Qiuli Mao , Xupeiyao Shi , Zheng Gao , Xiaoning Wang , Hanlin Guo , Lingxiao Chen , Yi Han , Ximing Li , Liyuan Chen , Siqi Tang , Ying Fan , Wenbing Yao , Hong Tian , Xiangdong Gao

Journal: J Control Release

PubMed ID: 39894265

Doi: 10.1016/j.jconrel.2025.01.094

Products & Services: Gene Synthesis

Respiratory syncytial virus glycoprotein G impedes CX3CR1-activation by CX3CL1 and monocyte function

Authors: Robert Meineke, Ayse Agac, Marie-Christin Knittler, Martin Ludlow, Albert D. M. E. Osterhaus & Guus F. Rimmelzwaan

Journal: npj viruses

Doi: doi.org/10.1038/s44298-024-00075-9

Products & Services: Gene Synthesis Mutagenesis Services

Cryo-EM structure of Nipah virus RNA polymerase complex

Authors: Yiru Wang, Lixia Zhao, Yi Zhang, Yuhan Wang, Jiao Tang, Simiao Liu, Huihan Gao, Xiaoxiao Zhang, Luca Zinzula, Roger D Kornberg, Heqiao Zhang

Journal: Science Advances