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Comparison of Cas12a and Cas9-mediated mutagenesis in tomato cells

Authors: Ellen Slaman, Lisanne Kottenhagen, William de Martines, Gerco C Angenent, Ruud A de Maagd

Journal: Sci Rep

PubMed ID: 38402312

Doi: 10.1038/s41598-024-55088-4

Products & Services: Gene Synthesis

A novel vaccine strategy using quick and easy conversion of bacterial pathogens to unnatural amino acid-auxotrophic suicide derivatives

Authors: Yuya Nagasawa, Momoko Nakayama, Yusuke Kato, Yohsuke Ogawa, Swarmistha Devi Aribam, Yusaku Tsugami, Taketoshi Iwata, Osamu Mikami, Aoi Sugiyama, Megumi Onishi, Tomohito Hayashi, Masahiro Eguchi

Journal: Microbiol Spectr

PubMed ID: 38385737

Doi: 10.1128/spectrum.03557-23

Products & Services: Gene Synthesis

Chronic exposure to parabens promotes non-alcoholic fatty liver disease in association with the changes of the gut microbiota and lipid metabolism

Authors: Yilin Ren, Xinyi Shi, Jing Mu, Shenyin Liu, Xin Qian, Wenlong Pei, Shanhong Ni, Zhengduo Zhang, Lei Li, Zhan Zhang

Journal: Food Funct

PubMed ID: 38236135

Doi: 10.1039/d3fo04347a

Products & Services: Gene Synthesis

Extracellular vesicles incorporating retrovirus-like capsids for the enhanced packaging and systemic delivery of mRNA into neurons

Authors: Wenchao Gu, Sijin Luozhong, Simian Cai, Ketaki Londhe, Nadine Elkasri, Robert Hawkins, Zhefan Yuan, Kai Su-Greene, Yujie Yin, Margaret Cruz, Yu-Wei Chang, Patrick McMullen, Chunyan Wu, Changwoo Seo, Akash Guru, Wenting Gao, Tara Sarmiento, Chris Schaffer, Nozomi Nishimura, Richard Cerione, Qiuming Yu, Melissa Warden, Robert Langer, Shaoyi Jiang

Journal: Nat Biomed Eng

PubMed ID: 38374224

Doi: 10.1038/s41551-023-01150-x

Products & Services: Gene Synthesis

Characterization of core oligosaccharide synthesis reveals novel aspects of lipooligosaccharide assembly

Authors: Leah M VanOtterloo, Luis A Macias, Matthew J Powers, Jennifer S Brodbelt, M Stephen Trent

Journal: MBio

PubMed ID: 38349180

Doi: 10.1128/mbio.03013-23

Products & Services: Gene Synthesis

Increasing β-hexosaminidase A activity using genetically modified mesenchymal stem cells

Authors: Alisa A Shaimardanova , Daria S Chulpanova , Valeriya V Solovyeva 1, Shaza S Issa , Aysilu I Mullagulova , Angelina A Titova , Yana O Mukhamedshina , Anna V Timofeeva , Alexander M Aimaletdinov , Islam R Nigmetzyanov , Albert A Rizvanov

Journal: Neural Regen Res .

PubMed ID: 37488869

Doi: 10.4103/1673-5374.375328

Products & Services: Gene Synthesis

TREM2 variants that cause early dementia and increase Alzheimer's disease risk affect gene splicing

Authors: Kostantin Kiianitsa, Maria E Lukes, Brian J Hayes, Julianna Brutman, Paul N Valdmanis, Thomas D Bird, Wendy H Raskind, Olena Korvatska

Journal: Brain

PubMed ID: 38226698

Doi: 10.1093/brain/awae014

Products & Services: Gene Synthesis Mutagenesis Services Plasmid DNA Preparation

Glyoxylate reductase: Definitive identification in human liver mitochondria, its importance for the compartment-specific detoxification of glyoxylate

Authors: Sander F Garrelfs, Serhii Chornyi, Heleen Te Brinke, Jos Ruiter, Jaap Groothoff, Ronald J A Wanders