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Larger active site in an ancestral hydroxynitrile lyase increases catalytically promiscuous esterase activity
Authors: View ORCID ProfileBryan J. Jones, View ORCID ProfileRobert L. Evans III, Nathan J. Mylrea, Debayan Chaudhury, Christine Luo, View ORCID ProfileBo Guan, View ORCID ProfileColin T. Pierce, View ORCID ProfileWendy R. Gordon, View ORCID ProfileCarrie M. Wilmot, View ORCID ProfileRomas J. Kazlauskas
Journal: biorxiv
Doi: 10.1101/2020.04.06.027797
Products & Services: Gene Synthesis   
Dissociation between the critical role of ClpB of Francisella tularensis for the heat shock response and the DnaK interaction and its important role for efficient …
Authors: Athar Alam , Igor Golovliov , Eram Javed , Rajender Kumar , Jörgen Ådén , Anders Sjöstedt
Journal: PLoS Pathog
PubMed ID: 32275693
Doi: 10.1371/journal.ppat.1008466
Products & Services: Gene Synthesis   
Effect of CRISPR/Cas9-Mediated PD-1-Disrupted Primary Human Third-Generation CAR-T Cells Targeting EGFRvIII on In Vitro Human Glioblastoma Cell Growth
Authors: Nakazawa T, Natsume A, Nishimura F, Morimoto T, Matsuda R, Nakamura M, Yamada S, Nakagawa I, Motoyama Y, Park YS, Tsujimura T, Wakabayashi T, Nakase H
Journal: Cells
PubMed ID: 32316275
Doi: 10.3390/cells9040998
Products & Services: Gene Synthesis   
Chk1-mediated phosphorylation of Cdh1 promotes the SCFβTRCP-dependent degradation of Cdh1 during S-phase and efficient cell-cycle progression.
Authors: Pal D,Torres AE,Stromberg BR,Messina AL,Dickson AS,De K,Willard B,Venere M,Summers MK
Journal: Cell death & disease
PubMed ID: 32345958
Doi: 10.1038/s41419-020-2493-1
Products & Services: Gene Synthesis   
Substrate specificity of the galactokinase from the human gut symbiont Akkermansia muciniphila ATCC BAA-835
Authors: Xunlian Zhang, Weihao Sheng, Kun Li, Yongheng Rong, Qizheng Wu, Qingyun Meng, Yun Kong, Min Chen
Journal: Enzyme and Microbial Technology
Doi: 10.1016/j.enzmictec.2020.109568
Products & Services: Gene Synthesis   
An amyloidogenic hexapeptide from the cataract-associated γD-crystallin is a model for the full-length protein and is inhibited by naphthoquinone-tryptophan hybrids
Authors: Abu-Hussien M, Viswanathan GK, Haj E, Paul A, Gazit E, Segal D
Journal: Int J Biol Macromol
PubMed ID: 32302630
Doi: 10.1016/j.ijbiomac.2020.04.079
Products & Services: Gene Synthesis   
Expression of recombinant apopholasin using a baculovirus–silkworm multigene expression system and activation via dehydrocoelenterazine
Authors: Moriguchi M, Takahashi R, Kang B1, Kuse M
Journal: Bioorg Med Chem Lett
PubMed ID: 32284275
Doi: 10.1016/j.bmcl.2020.127177
Products & Services: Gene Synthesis   
Phosphorylation of vaccinia-related kinase 1 at threonine 386 transduces glucose stress signal in human liver cells
Authors: Kosuke Yokobori, Yuu Miyauchi, Jason G Williams, Masahiko Negishi
Journal: Biosci Rep
PubMed ID: 32266931
Doi: 10.1042/BSR20200498
Products & Services: Gene Synthesis   
Immunogenicity and protection induced by recombinant Toxocara canis proteins in a murine model of toxocariasis
Authors: Luis FabiánSalazar GarcésaLeonardo FreireSantiagoaSara Patrícia de OliveiraSantosaDumar AlexanderJaramillo HernándezacMarcia Barbosada SilvaaVitor dos SantosAlvesaElisania FontesSilveiraaStella MariaBarrouin-MelobPhilip JohnCooperdeLuis Gustavo CarvalhoPachecoaCarina da SilvaPinheiroaNeuza MariaAlcantara-Neves
Journal: Vaccine
Doi: 10.1016/j.vaccine.2020.04.072
Products & Services: Gene Synthesis   
CRISPR/Cas9-based inactivation of human papillomavirus oncogenes E6 and E7 induces senescence in cervical cancer cells
Authors: Raviteja Inturi;View ORCID ProfilePer Jemth 6
Journal: biorxiv
Doi: 10.1101/2020.04.16.044446
Products & Services: Gene Synthesis   
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