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Loss of APJ mediated β-arrestin signalling improves high-fat diet induced metabolic dysfunction but does not alter cardiac function in mice

Authors: Li N, Ma X, Ban T, Xu S, Ma Y, Ason B, Hu LA

Journal: The Biochemical journal

PubMed ID: 32779693

Doi: 10.1042/BCJ20200343

Products & Services: Gene Synthesis

Targeting RSPO3-LGR4 Signaling for Leukemia Stem Cell Eradication in Acute Myeloid Leukemia

Authors: Salik B, Yi H, Hassan N, Santiappillai N, Vick B, Connerty P, Duly A, Trahair T, Woo AJ, Beck D, Liu T, Spiekermann K, Jeremias I, Wang J, Kavallaris M, Haber M, Norris MD, Liebermann DA, D'Andrea RJ, Murriel C, Wang JY

Journal: Cancer Cell

PubMed ID: 32559496

Doi: 10.1016/j.ccell.2020.05.014

Products & Services: Gene Synthesis

Elevated Serum Amino Acids Induce a Subpopulation of Alpha Cells to Initiate Pancreatic Neuroendocrine Tumor Formation

Authors: Smith DK, Kates L, Durinck S, Patel N, Stawiski EW, Kljavin N, Foreman O, Sipos B, Solloway MJ, Allan BB, Peterson AS

Journal: Cell reports. Medicine

PubMed ID: 33205067

Doi: 10.1016/j.xcrm.2020.100058

Products & Services: Gene Synthesis

Distinct Calcium Binding and Structural Properties of Two Centrin Isoforms from Toxoplasma gondii

Authors: Luca Bombardi, Marco Pedretti, Carolina Conter, Paola Dominici, Alessandra Astegno

Journal: Biomolecules

PubMed ID: 32759683

Doi: 10.3390/biom10081142

Products & Services: Gene Synthesis

Increase in Toxicity of Anticancer Drugs by PMTPV, a Claudin-1-Binding Peptide, Mediated via Down-Regulation of Claudin-1 in Human Lung Adenocarcinoma A549 Cells

Authors: Nasako H, Takashina Y, Eguchi H, Ito A, Ishikawa Y, Matsunaga T, Endo S, Ikari A

Journal: International Journal of Molecular Sciences

PubMed ID: 32824620

Doi: 10.3390/ijms21165909

Products & Services: Gene Synthesis

Hydrophobic interactions between the HA helix and S4-S5 linker modulate apparent Ca 2+ sensitivity of SK2 channels

Authors: Young-Woo Nam, Meng Cui, Razan Orfali, Adam Viegas, Misa Nguyen, Eman H M Mohammed, Khalid A Zoghebi, Simin Rahighi, Keykavous Parang, Miao Zhang

Journal: Acta Physiol (Oxf)

PubMed ID: 32865319

Doi: 10.1111/apha.13552

Products & Services: Gene Synthesis

Lipocalin-2 Exacerbates Lupus Nephritis by Promoting Th1 Cell Differentiation.

Authors: Chen W,Li W,Zhang Z,Tang X,Wu S,Yao G,Li K,Wang D,Xu Y,Feng R,Duan X,Fan X,Lu L,Chen W,Li C,Sun L

Journal: Journal of the American Society of Nephrology : JASN

PubMed ID: 32646856

Doi: 10.1681/ASN.2019090937

Products & Services: Gene Synthesis

Real-time detection of changes in yeast plasma membrane potential using genetically encoded voltage indicator proteins

Authors: Limapichat W, Pornthanakasem W, Satitthammachart C, Chitnumsub P, Leartsakulpanich U

Journal: FEMS yeast research

PubMed ID: 32691845

Doi: 10.1093/femsyr/foaa041

Products & Services: Gene Synthesis

Histone H33 phosphorylation amplifies stimulation-induced transcription

Authors: Armache A, Yang S, Martínez de Paz A, Robbins LE, Durmaz C, Cheong JQ, Ravishankar A, Daman AW, Ahimovic DJ, Klevorn T, Yue Y, Arslan T, Lin S, Panchenko T, Hrit J, Wang M, Thudium S, Garcia BA, Korb E, Armache KJ, Rothbart SB, Hake SB, Allis CD, Li H, Josefowicz SZ

Journal: Nature

PubMed ID: 32699416

Doi: 10.1038/s41586-020-2533-0

Products & Services: Gene Synthesis

The proofreading activity of Pfprex from Plasmodium falciparum can prevent mutagenesis of the apicoplast genome by oxidized nucleotides

Authors: Sharma M, Narayanan N, Nair DT

Journal: Scientific REPORTS

PubMed ID: 32636411

Doi: 10.1038/s41598-020-67853-2

Products & Services: Gene Synthesis