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Toxicological and pharmacological assessment of AGEN1884, a novel human IgG1 anti-CTLA-4 antibody

PLoS ONE. 2018-01; 
Gombos RB, Gonzalez A, Manrique M, Chand D, Savitsky D, Morin B, Breous-Nystrom E, Dupont C, Ward RA, Mundt C, Duckless B, Tang H, Findeis MA, Schuster A, Waight JD, Underwood D, Clarke C, Ritter G, Merghoub T, Schaer D, Wolchok JD, van Dijk M, Buell JS, Cuillerot JM, Stein R, Drouin EE, Wilson NS
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Gene Synthesis Cell-based ligand blocking assay CTLA-4 expressing CHO cells (GenScript; catalogue (Promega) were co-cultured with a FcγRIIIA (158V vari- ant)-expressing NK-92 cell line (Genscript or an isotype control antibody Get A Quote

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