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Upregulating DAB2IP expression via EGR-1 inhibition, a new approach for overcoming fractionated-irradiation-induced cross-tolerance to ionizing radiation and mitomycin C in tumor cells.

Int. J. Radiat. Biol.. 2017; 
Chang Rulve,He Hui,Mao Guangmin,Kong Zh
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Gene Synthesis The primers of all target genes were mentioned previously (Wu et al. 2013; Yun et al. 2015) and designed by GenScript (Nanjing, Jiangsu, China). Get A Quote

摘要

To evaluate the effect of fractionated irradiation (FI) on tumor cells' sensitivity to ionizing radiation (IR) and antineoplastic drugs, and examine the potential of early growth response-1 (EGR-1) inhibition to sensitize tumor cells to IR.

关键词

DAB2IP,EGR-1,fractionated irradiation,radioresist