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Deep learning using tumor HLA peptide mass spectrometry datasets improves neoantigen identification.

Nat. Biotechnol.. 2018;

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Products/Services Used	Details	Operation
Gene Synthesis	Custom-made, recombinant lyophilized peptides were purchased from JPT Peptide Technologies (Berlin, Germany) or Genscript (Piscataway, NJ, USA) and reconstituted at 10–50 mM in sterile DMSO (VWR International, Pittsburgh, PA, USA), aliquoted and stored at −80 °C. The top 20 (seven patients) or top 10 (two patients with limited PBMC availability) peptides across the top 20 ranked mutations per patient were selected using an earlier training iteration of the full MS model available at time of sample processing.	Get A Quote

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Deep learning using tumor HLA peptide mass spectrometry datasets improves neoantigen identification.

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