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Methylenetetrahydrofolate reductase gene polymorphism， homocysteine and risk of macroangiopathy in Type 2 diabetes mellitus.

J. Endocrinol. Invest.. 2006; 
SunJ，XuY，ZhuY
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Gene Synthesis … Approximately 120 ng of genomic DNA was incubated in a total reaction mixture of 20 μL containing both the forward primer 5′ TGAAGGAGAAGGTGTCTGCGGGA 3′ and reverse primer 5′ AGGACGGTGCGGTGAGAGTG 3′ (~ 10picomoles) (GenScript Corp, USA), 200 μM … Get A Quote

摘要

A polymorphism in the gene for methylenetetrahydrofolate reductase (MTHFR) has been reported to be associated with hyperhomocysteinemia and risk for atherosclerotic vascular diseases. In this case-control study， we examined the distribution of the MTHFR genotypes in the Chinese population and clarified the relationship between the gene polymorphism for MTHFR and macroangiopathy in Chinese Type 2 diabetes mellitus.

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