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Long noncoding RNA CCAT1 promotes hepatocellular carcinoma progression by functioning as let-7 sponge.

J. Exp. Clin. Cancer Res.. 2015-02; 
DengLiang，YangShi-Bin，XuFeng-Feng，ZhangJi-
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Gene Synthesis … CCCAAGCTTAAGACTTAATATACTTATATTTA-3′ (reverse) The pcDNA31-CCAT1 with point mutations in let-7 binding sites was synthesized by GenScript (Nanjing, China) and named pcDNA31-CCAT1-Mut pSL-MS2-12X … Get A Quote

摘要

Long noncoding RNAs (lncRNAs) have been identified as having functional roles in cancer biology and are deregulated in many cancers. The present study aimed to determine the expression， roles and functional mechanisms of a long noncoding RNA CCAT1 in the progression of hepatocellular carcinoma (HCC).

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