Lentiviral vectors can be used for full-length dystrophin gene therapy
Products/Services Used |
Details |
Operation |
Gene Synthesis> |
The stuffer sequence is a contiguous fusion of various transgenes whose extreme termini have been deleted to render them dysfunctional, should any transcription initiate from a cryptic promoter. Potential splice sites and polyadenylation sequences were identified and removed using SplicePort47. The stuffer was synthesised by and purchased from GenScript (NJ, USA). |
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