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Linc00152 promotes malignant progression of glioma stem cells by regulating miR-103a-3p/FEZF1/CDC25A pathway.

Mol. Cancer. 2017; 
YuMingjun，XueYixue，ZhengJian，LiuXiaobai，YuHai，LiuLibo，LiZhen，LiuYu
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Plasmid DNA Preparation Short-hairpin RNA directed against human linc00152 plasmid (sh-linc00152), short-hairpin RNA directed against human FEZF1 plasmid (FEZF1(−)), short-hairpin RNA Yu et al. Molecular Cancer (2017) 16:110 Page 14 of 18directed against human CDC25A plasmid (CDC25A(−)) and their respective non-targeting sequence (negative control, NC) were synthesized (GenePharma, Shanghai, China). FEZF1 full length (FEZF1(+)) plasmid, CDC25A full length (CDC25A(+)) plasmid, and their respective non-targeting sequence (negative control, NC) were synthesized (GenScript, Piscataway, NJ, USA). Get A Quote

摘要

Glioma is one of the most frequent intracranial malignant tumors. LncRNAs have been identified as new modulators in the origination and progression of glioma.

关键词

CDC25A，FEZF1，Glioma stem cells，Long non-coding RNA，linc00152，miR-103
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