3-Hydroxypropionic acid (3-HP) is an important platform chemical， serving as a precursor for a wide range of industrial applications such as the production of acrylic acid and 1，3-propanediol. Although Escherichia coli or Saccharomyces cerevisiae are the primary industrial microbes for the production of 3-HP， alternative engineered hosts have the potential to generate 3-HP from other carbon feedstocks. Methylobacterium extorquens AM1， a facultative methylotrophic α-proteobacterium， is a model system for assessing the possibility of generating 3-HP from one-carbon feedstock methanol.
3-Hydroxypropionic acid (3-HP) is an important platform chemical， serving as a precursor for a wide range of industrial applications such as the production of acrylic acid and 1，3-propanediol. Although Escherichia coli or Saccharomyces cerevisiae are the primary industrial microbes for the production of 3-HP， alternative engineered hosts have the potential to generate 3-HP from other carbon feedstocks. Methylobacterium extorquens AM1， a facultative methylotrophic α-proteobacterium， is a model system for assessing the possibility of generating 3-HP from one-carbon feedstock methanol.
