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Accuracy of chimeric proteins in the serological diagnosis of chronic chagas disease - a Phase II study

PLoS Negl Trop Dis. 2017-03; 
SantosFred Luciano Neves, CeledonPaola Alejandra Fiorani, ZanchinNilson Ivo Tonin, de SouzaWayner Vieira, da SilvaEdimilson Domingos, FotiLeonardo, KriegerMarco Aurélio, GomesYara de Mir
Products/Services Used Details Operation
Gene Synthesis … [9] (further information see S1 Table). Briefly, synthetic genes encoding T. cruzi chimeric antigens were obtained from a commercial supplier (GenScript, Piscataway, NJ, USA) and subcloned into the pET28a vector. Chimeric … Get A Quote

摘要

The performance of current serologic tests for diagnosing chronic Chagas disease (CD) is highly variable. The search for new diagnostic markers has been a constant challenge for improving accuracy and reducing the number of inconclusive results.

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