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Quantitative Real-Time Imaging of Glutathione with Sub-Cellular Resolution.

Antioxid. Redox Signal.. 2018-10; 
JiangXiqian，ZhangChengwei，ChenJianwei，ChoiSungwoo，ZhouYing，ZhaoMingkun，SongXianzhou，ChenXi，Maletic-SavaticMirjana，PalzkillTimothy Gerald，MooreDavid，WangMeng C，Wan
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Gene Synthesis … cytoplasm specific. Whole piece of DNA fragment, including signal sequence and Halo cDNA sequence, was synthesized by Genscript, and then inserted into pCDNA 3.1 (+) vector through KpnI (5'end) and NotI (3'end) sites. HeLa … Get A Quote

摘要

Quantitative imaging of glutathione with high spatial and temporal resolution is essential for studying the roles of glutathione in redox biology. To study the long-standing question of compartmentalization of glutathione， especially its distribution between the nucleus and the cytosol， an organelle-targeted quantitative probe is needed.

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