| ￥3300 | |
| Z05932-100 | |
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| Species | Human | ||||
| Protein Construction |
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| Purity | > 95% as determined by BisTris PAGE | ||||
| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||
| Biological Activity | Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch. | ||||
| Expression System | HEK293 | ||||
| Theoretical Molecular Weight | 50.8 kDa | ||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 60-75 kDa based on Bis-Tris PAGE result. | ||||
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). | ||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
Immobilized Human TSLP (R127A, R130A), His Tag at 2 μg/ml(100 μl/well) on the plate. Dose response curve for TSLPR hFc Chimera, Human, hFc Tag with the EC50 of 4.1ng/ml determined by ELISA. »
Immobilized TSLPR hFc Chimera, Human, hFc Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-TSLPR Antibody, hFc Tag with the EC50 of 26.1ng/ml determined by ELISA. »
The purity of TSLPR hFc Chimera, Human is greater than 95% as determined by SEC-HPLC. »
TSLPR hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »
Human TSLP, His Tag captured on CM5 Chip via Anti-His Antibody can bind TSLPR hFc Chimera, Human, hFc Tag with an affinity constant of 1.04 nM as determined in SPR assay (Biacore T200). »
| Target Background | Thymic stromal lymphopoietin (TSLP) is an interleukin-7 (IL-7) like cytokine, which plays an important role in the regulation of immune responses to allergens. TSLP binds to a heterodimeric receptor complex composed of the IL-7 receptor alpha chain (IL-7Ralpha) and the TSLP receptor (TSLPR, also known as CRLF2). |
| Synonyms | TSLP receptor; TSLPR; CRL2; CRLF2Y; CRLF2; IL-XR; p2RY8/CRLF2 fusion; CRLF2 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
