| ￥3000 | |
| Z05644-100 | |
|
|
|
|
|
|
|
|
|
| Species | Human | ||||
| Protein Construction |
|
||||
| Purity | > 95% as determined by BisTris PAGE | ||||
| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||
| Biological Activity | Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch. | ||||
| Expression System | HEK293 | ||||
| Theoretical Molecular Weight | 78.9 kDa | ||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 115-140 kDa based on Bis-Tris PAGE result. | ||||
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). | ||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
Immobilized MERTK/Mer mFc Chimera, Human, mFc Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Human GAS6, His Tag with the EC50 of 2.14 μg/ml determined by ELISA. »
The purity of MERTK/Mer mFc Chimera, Human is greater than 95% as determined by SEC-HPLC. »
MERTK/Mer mFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »
| Target Background | MER tyrosine kinase (MERTK) encodes a surface receptor localized at the apical membrane of the retinal pigment epithelium. It plays a critical role in photoreceptor outer segment internalization prior to phagocytosis. Mutations in MERTK have been associated with severe autosomal recessive retinal dystrophies in the RCS rat and in humans. |
| Synonyms | MERTK; MER; c-Eyk; MGC133349; c-mer; RP38; Tyro12 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
