| ￥3500 | |
| Z04937-100 | |
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| Species | Cynomolgus | ||||
| Protein Construction |
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| Purity | > 95% as determined by BisTris PAGE | ||||
| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||
| Biological Activity | Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch. | ||||
| Expression System | HEK293 | ||||
| Theoretical Molecular Weight | 16.3 kDa | ||||
| Apparent Molecular Weight | Due to furin cleavage site, the protein migrates to 12 kDa&23-30 kDa based on Bis-Tris PAGE result. | ||||
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). | ||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
Loaded TSLP, His, Cynomolgus, hFc Tag on ProA-Biosensor can bind Cynomolgus TSLP, His Tag with an affinity constant of 6.58 nM as determined in BLI assay (Gator® Prime). »
Loaded Anti-TSLP Antibody, hFc Tag on ProA-Biosensor can bind TSLP, His, Cynomolgus, His Tag with an affinity constant of 2.02 nM as determined in BLI assay (Gator® Prime). »
Immobilized TSLP, His, Cynomolgus, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Human TSLPR, hFc Tag with the EC50 of 4.0ng/ml determined by ELISA. »
Immobilized TSLP, His, Cynomolgus, His Tag at 1 μg/ml(100 μl/well) on the plate. Dose response curve for Anti-TSLP Antibody, hFc Tag with the EC50 of 6.2ng/ml determined by ELISA. »
The purity of TSLP, His, Cynomolgus is greater than 90% as determined by SEC-HPLC. »
TSLP, His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »
| Target Background | Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c dendritic cells. Can induce allergic inflammation by directly activating mast cells. |
| Synonyms | thymic stromal lymphopoietin; TSLP |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
