| ￥5800 | |
| Z04570-100 | |
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| Species | Human | ||||||
| Protein Construction |
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| Conjugate | Biotin | ||||||
| Purity | > 95% as determined by BisTris PAGE | ||||||
| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||||
| Biological Activity | Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch. | ||||||
| Expression System | HEK293 | ||||||
| Theoretical Molecular Weight | 20 kDa | ||||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 26-45 kDa based on Bis-Tris PAGE result. | ||||||
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). | ||||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||||
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
Immobilized Biotinylated NKp30/NCR3/CD337[Biotin], His & Avi, Human, His-Avi Tag at 0.5 μg/ml (100 μl/Well) on streptavidin(5 μg/ml) precoated plate. Dose response curve for Anti-NKp30 Antibody, hFc Tag with the EC50 of 4.3ng/ml determined by ELISA. »
The purity of NKp30/NCR3/CD337[Biotin], His & Avi, Human is greater than 95% as determined by SEC-HPLC. »
NKp30/NCR3/CD337[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »
Human B7-H6, hFc Tag captured on CM5 Chip via Protein A can bind Biotinylated NKp30/NCR3/CD337[Biotin], His & Avi, Human, His-Avi Tag with an affinity constant of 0.330 μM as determined in SPR assay (Biacore T200). »
| Target Background | NKp30, along with NKp44 and NKp46, constitute a group of receptors termed 'Natural Cytotoxicity Receptors'. These receptors play a major role in triggering NK-mediated killing of most tumor cells lines.NKp30 stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. |
| Synonyms | CD337; LY117; NCR3; NKp30; 1C7; MALS |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
