| ￥1200 | |
| A02438-50 | |
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| Specificity | This product is specific to Cytokeratin 18 |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human Cytokeratin 18 |
| Species Reactivity | Human |
| Conjugate | Unconjugated |
| Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product. | |||||||||||||
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| Form | Liquid |
| Storage Buffer | Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Storage Instructions | Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed. |
| Purification | Affinity-chromatography |
| Isotype | Rabbit IgG |
| Clonality | Monoclonal |
Western blot analysis of Cytokeratin 18 expression in (1) HT-29 cell lysate;(2) human kidney lysate. »
| Target Background | Involved in the uptake of thrombin-antithrombin complexes by hepatic cells. When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection. |
| Synonyms | Keratin-18; CYK18; cytokeratin 18; Cytokeratin-18; K18; K1C18; keratin 18; KRT18; CK-18; |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
