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The shift of macrophages toward M1 phenotype promotes aortic valvular calcification

J. Thorac. Cardiovasc. Surg.. 2017-06; 
LiGeng, QiaoWeihua, ZhangWenjing, LiFei, ShiJiawei, DongNia
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Gene Synthesis … Quantitative Real-Time Polymerase Chain Reaction. The RNA was isolated and reversely transcribed to cDNA as previously described. 16 Primers were purchased from GenScript Co, Ltd (Nanjing, China). Sequences for all quantitative PCR primers are shown in Table E1 … Get A Quote

摘要

The purpose of the present study was to comprehensively compare the phenotype profile of infiltrated macrophages in human noncalcified and calcific aortic valves， and to determine whether the shift of macrophage polarization modulates valvular calcification in vitro.

关键词

calcific aortic valve disease，calcification，macrophage polarization，valve interstitial
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